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STRMU:Q8DS93

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Species (Taxon ID) Streptococcus mutans serotype c (strain ATCC 700610 / UA159). (210007)
Gene Name(s) comE (ECO:0000313 with EMBL:AAN59528.1)
Protein Name(s) Putative response regulator of the competence regulon, ComE response regulator of sakacin A production (ECO:0000313 with EMBL:AAN59528.1)
External Links
UniProt Q8DS93
EMBL AE014133
RefSeq NP_722222.1
ProteinModelPortal Q8DS93
STRING 210007.SMU.1917
EnsemblBacteria AAN59528
GeneID 1029114
KEGG smu:SMU_1917
PATRIC 19665797
KO K07707
OMA ELFSHRI
OrthoDB EOG6VXFD9
PhylomeDB Q8DS93
BioCyc SMUT210007:GC7Z-1807-MONOMER
Proteomes UP000002512
GO GO:0003677
GO:0000160
GO:0006355
GO:0006351
InterPro IPR011006
IPR007492
IPR001789
Pfam PF04397
PF00072
SMART SM00850
SM00448
SUPFAM SSF52172
PROSITE PS50930
PS50110

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0045892

negative regulation of transcription, DNA-templated

PMID:17526837[1]

ECO:0000315

P

Figure 2a shows the expression levels of comC in the wild type samples and the comE mutant samples. The wild type samples only showed an increase in comC when grown in the presence of CSP, whereas comE mutants showed high expression levels of comC, even those that were not grown in the presence of CSP.

complete
CACAO 9793

involved_in

GO:0045892

negative regulation of transcription, DNA-templated

PMID:17526837[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0000160

phosphorelay signal transduction system

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001789

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR007492

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Kreth, J et al. (2007) The response regulator ComE in Streptococcus mutans functions both as a transcription activator of mutacin production and repressor of CSP biosynthesis. Microbiology (Reading, Engl.) 153 1799-807 PubMed GONUTS page