STRMU:LUXS

Species (Taxon ID)	Streptococcus mutans serotype c (strain ATCC 700610 / UA159). (210007)
Gene Name(s)	luxS (ECO:0000255 with HAMAP-Rule:MF_00091)
Protein Name(s)	S-ribosylhomocysteine lyase (ECO:0000255 with HAMAP-Rule:MF_00091) AI-2 synthesis protein (ECO:0000255 with HAMAP-Rule:MF_00091) Autoinducer-2 production protein LuxS (ECO:0000255 with HAMAP-Rule:MF_00091)
External Links
UniProt	Q8DVK8
EMBL	AE014133
RefSeq	NP_720916.1
ProteinModelPortal	Q8DVK8
STRING	210007.SMU.474
EnsemblBacteria	AAN58222
GeneID	1027971
KEGG	smu:SMU_474
PATRIC	19663167
eggNOG	COG1854
KO	K07173
OMA	KQPNQDH
OrthoDB	EOG68WRBM
PhylomeDB	Q8DVK8
BioCyc	SMUT210007:GC7Z-472-MONOMER
Proteomes	UP000002512
GO	GO:0005506 GO:0043768 GO:0009372
Gene3D	3.30.1360.80
HAMAP	MF_00091
InterPro	IPR011249 IPR003815
Pfam	PF02664
PIRSF	PIRSF006160
PRINTS	PR01487
ProDom	PD013172
SUPFAM	SSF63411

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0009369	quorum sensing signal generator activity	PMID:12654815	ECO:0000316		UniProtKB:P45578	1		Figure 2: A plasmid containing the luxS gene from S. mutans complements the mutation in AI-2 producing deficient E. coli strain DH5alpha, showing that the LuxS protein in S. mutans produces AI-2	complete
	GO:0044011	single-species biofilm formation on inanimate substrate	PMID:12654815	ECO:0000315			P		Figure 5: luxS mutants of S. mutans form altered biofilms, that are more suceptible to SDS	complete
enables	GO:0003824	catalytic activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011249	F		Seeded From UniProt	complete
enables	GO:0005506	iron ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003815 InterPro:IPR037005	F		Seeded From UniProt	complete
involved_in	GO:0009372	quorum sensing	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003815 InterPro:IPR037005	P		Seeded From UniProt	complete
enables	GO:0043768	S-ribosylhomocysteine lyase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003815 InterPro:IPR037005	F		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011249	F		Seeded From UniProt	complete
enables	GO:0043768	S-ribosylhomocysteine lyase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:4.4.1.21	F		Seeded From UniProt	complete
enables	GO:0043768	S-ribosylhomocysteine lyase activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000076351	F		Seeded From UniProt	complete
involved_in	GO:0009372	quorum sensing	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000076351	P		Seeded From UniProt	complete
enables	GO:0016829	lyase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0456	F		Seeded From UniProt	complete
involved_in	GO:0009372	quorum sensing	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0673	P		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
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References

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