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STRMU:GAPN

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Species (Taxon ID) Streptococcus mutans serotype c (strain ATCC 700610 / UA159). (210007)
Gene Name(s) gapN
Protein Name(s) NADP-dependent glyceraldehyde-3-phosphate dehydrogenase

Glyceraldehyde-3-phosphate dehydrogenase [NADP(+)] Non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase Triosephosphate dehydrogenase

External Links
UniProt Q59931
EMBL L38521
AE014133
PIR A57151
RefSeq NP_721104.1
PDB 1EUH
1QI1
1QI6
2ESD
2EUH
2ID2
2QE0
PDBsum 1EUH
1QI1
1QI6
2ESD
2EUH
2ID2
2QE0
ProteinModelPortal Q59931
SMR Q59931
STRING 210007.SMU.676
EnsemblBacteria AAN58410
GeneID 1028095
KEGG smu:SMU_676
PATRIC 19663537
eggNOG COG1012
KO K00131
OMA YVYASAK
OrthoDB EOG6BS8QW
PhylomeDB Q59931
BioCyc MetaCyc:MONOMER-13095
SMUT210007:GC7Z-660-MONOMER
SABIO-RK Q59931
EvolutionaryTrace Q59931
Proteomes UP000002512
GO GO:0008886
Gene3D 3.40.309.10
3.40.605.10
InterPro IPR016161
IPR016163
IPR016160
IPR016162
IPR015590
Pfam PF00171
SUPFAM SSF53720
PROSITE PS00070

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0047100

glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity

PMID:24032678[1]

ECO:0000314

F

Fig. 3 shows NADP+-induced restoration catalytic activity after thermal inactivation.

complete
CACAO 8698

enables

GO:0047100

glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity

PMID:24032678[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015590
InterPro:IPR016160
InterPro:IPR016161
InterPro:IPR016162
InterPro:IPR016163

F

Seeded From UniProt

complete

enables

GO:0016620

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016163

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR015590
InterPro:IPR016160
InterPro:IPR016161
InterPro:IPR016162
InterPro:IPR016163

P

Seeded From UniProt

complete

enables

GO:0008886

glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:1.2.1.9

F

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Arutyunov, D et al. (2013) An unusual effect of NADP+ on the thermostability of the nonphosphorylating glyceraldehyde-3-phosphate dehydrogenase from Streptococcus mutans. Biochem. Cell Biol. 91 295-302 PubMed GONUTS page