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STRAZ:Q8GGN5
Contents
| Species (Taxon ID) | Streptomyces atroolivaceus. (66869) | |
| Gene Name(s) | LnmQ (ECO:0000313 with EMBL:AAN85530.1) | |
| Protein Name(s) | Nonribosomal peptide synthetase, discrete adenylation domain (ECO:0000313 with EMBL:AAN85530.1) | |
| External Links | ||
| UniProt | Q8GGN5 | |
| EMBL | AF484556 | |
| ProteinModelPortal | Q8GGN5 | |
| GO | GO:0016874 | |
| InterPro | IPR010071 IPR025110 IPR020845 IPR000873 | |
| Pfam | PF00501 PF13193 | |
| TIGRFAMs | TIGR01733 | |
| PROSITE | PS00455 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
Contributes to |
GO:0019184 |
nonribosomal peptide biosynthetic process |
ECO:0000315 |
P |
Fig. 4B shows HPLC analysis of the formation of leinamycin. Mutants lacking lnmQ don't produce leinamycin. |
complete | ||||
| GO:0043042 |
amino acid adenylylation by nonribosomal peptide synthase |
ECO:0000314 |
P |
Fig. 2 shows the amino acid specificity and Michaelis-Menton kinetics of LnmQ. |
complete | |||||
|
involved_in |
GO:0043042 |
amino acid adenylylation by nonribosomal peptide synthase |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003824 |
catalytic activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016874 |
ligase activity |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Tang, GL et al. (2004) Leinamycin biosynthesis revealing unprecedented architectural complexity for a hybrid polyketide synthase and nonribosomal peptide synthetase. Chem. Biol. 11 33-45 PubMed GONUTS page
- ↑ 2.0 2.1 Tang, GL et al. (2007) Chain initiation in the leinamycin-producing hybrid nonribosomal peptide/polyketide synthetase from Streptomyces atroolivaceus S-140. Discrete, monofunctional adenylation enzyme and peptidyl carrier protein that directly load D-alanine. J. Biol. Chem. 282 20273-82 PubMed GONUTS page