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STALU:E6MC21

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Species (Taxon ID) Staphylococcus lugdunensis M23590. (525377)
Gene Name(s) isdC (ECO:0000313 with EMBL:EFU83527.1)
Protein Name(s) Heme uptake protein IsdC (ECO:0000313 with EMBL:EFU83527.1)
External Links
UniProt E6MC21
EMBL AEQA01000016
EnsemblBacteria EFU83527
PATRIC 45126722
GO GO:0009274
GO:0015886
InterPro IPR019909
IPR006635
IPR017505
Pfam PF05031
SMART SM00725
TIGRFAMs TIGR03656
TIGR03068
PROSITE PS50978

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0042710

biofilm formation

PMID:24686057[1]

IMP: Inferred from Mutant Phenotype

P

Figure 4 is able to demonstrate how one or more proteins expressed by the isd locus are involved in biofilm formation in iron deficient environments, due to the ability of the mutant with the isd locus deleted to produce the same amount of biofilm as the wild-type. The only mutant strand without the isd locus that shows growth on iron deficient media contains the IsdC protein. This illustrates the fact that IsdC is sufficient, all alone, in promoting biofilm formation in minimal iron conditions.

complete
CACAO 10084

GO:0009274

peptidoglycan-based cell wall

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019909

C

Seeded From UniProt

complete

GO:0015886

heme transport

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019909

P

Seeded From UniProt

complete

GO:0030492

hemoglobin binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019909

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Missineo, A et al. (2014) IsdC from Staphylococcus lugdunensis induces biofilm formation under low-iron growth conditions. Infect. Immun. 82 2448-59 PubMed GONUTS page