STAAU:G0Z026

Species (Taxon ID)	Staphylococcus aureus. (1280)
Gene Name(s)	selX (ECO:0000313 with EMBL:AEI60187.1)
Protein Name(s)	Enterotoxin-like toxin X (ECO:0000313 with EMBL:AEI60187.1)
External Links
UniProt	G0Z026
EMBL	HQ850970
GO	GO:0005576 GO:0009405
Gene3D	3.10.20.120
InterPro	IPR016091 IPR006123
Pfam	PF02876
SUPFAM	SSF54334

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0009405	pathogenesis	PMID:22022262	ECO:0000315			P		The experiment compared the ability of wild type, mutant and repaired strains to cause lethal necrotizing pneumonia in a rabbit model. As seen in figure 6c, animals receiving wild type LAC, all 11 rabbits succumbed within 4 days, compared to 2 of 11 receiving LAC Δselx. Importantly, 4 of 4 rabbits infected with the repaired strain LAC Δselx rep succumbed within 4 days. As seen in figure 6d, body temperatures were recorded in the first 24 h of the experiment, and animals receiving strain LAC demonstrated significantly higher body temperatures than animals receiving the SElX-deficient strain LAC Δselx and LAC Δselx rep had wild type levels of pyrogenicity.	complete CACAO 4218
involved_in	GO:0009405	pathogenesis	PMID:22022262	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016091	C		Seeded From UniProt	complete
involved_in	GO:0009405	pathogenesis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR016091	P		Seeded From UniProt	complete
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References

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