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SPHWW:MAND

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Species (Taxon ID) Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273). (392499)
Gene Name(s) No Information Provided.
Protein Name(s) D-mannonate dehydratase

ManD

External Links
UniProt A5V6Z0
EMBL CP000699
RefSeq WP_011952534.1
ProteinModelPortal A5V6Z0
SMR A5V6Z0
STRING 392499.Swit_1693
EnsemblBacteria ABQ68056
KEGG swi:Swit_1693
PATRIC 23682480
eggNOG ENOG4105CXK
COG4948
HOGENOM HOG000113758
KO K08323
OMA NQRAFEI
OrthoDB EOG6SBSZM
BioCyc SWIT392499:GHZK-1714-MONOMER
UniPathway UPA00246
Proteomes UP000001989
GO GO:0000287
GO:0008927
GO:0016052
GO:0009063
Gene3D 3.20.20.120
3.30.390.10
InterPro IPR029065
IPR029017
IPR018110
IPR013342
IPR013341
IPR001354
PANTHER PTHR13794
Pfam PF13378
PF02746
SMART SM00922
SUPFAM SSF51604
SSF54826
PROSITE PS00908

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0008927

mannonate dehydratase activity

PMID:24697546[1]

ECO:0000314

F

Table 1 has kcat/Km values for the dehydration of D-mannonate and gluconate. The value for gluconate is too small to make a confident prediction of function. But the value for D-mannonate is comparable to other enzymes known to catalyze that reaction.

complete
CACAO 10213

enables

GO:0008927

mannonate dehydratase activity

PMID:24697546[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0016052

carbohydrate catabolic process

PMID:24697546[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0000287

magnesium ion binding

PMID:24697546[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0009063

cellular amino acid catabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR018110

P

Seeded From UniProt

complete

enables

GO:0008927

mannonate dehydratase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:4.2.1.8

F

Seeded From UniProt

complete

involved_in

GO:0005975

carbohydrate metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0119

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0016829

lyase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0456

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Wichelecki, DJ et al. (2014) Discovery of function in the enolase superfamily: D-mannonate and d-gluconate dehydratases in the D-mannonate dehydratase subgroup. Biochemistry 53 2722-31 PubMed GONUTS page