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SHIFL:OSPF
Contents
| Species (Taxon ID) | Shigella flexneri. (623) | |
| Gene Name(s) | ospF (synonyms: mkaD) | |
| Protein Name(s) | Phosphothreonine lyase OspF
Effector protein OspF | |
| External Links | ||
| UniProt | Q8VSP9 | |
| EMBL | AL391753 AF348706 AY206429 AY879342 AF386526 DQ362850 DQ362864 DQ362865 DQ362866 DQ362867 DQ362868 DQ362869 DQ362870 | |
| RefSeq | NP_858143.1 WP_001121867.1 WP_010921598.1 YP_006960239.1 YP_009078261.1 | |
| PDB | 3I0U | |
| PDBsum | 3I0U | |
| ProteinModelPortal | Q8VSP9 | |
| SMR | Q8VSP9 | |
| IntAct | Q8VSP9 | |
| STRING | 198214.CP0010 | |
| PRIDE | Q8VSP9 | |
| EnsemblBacteria | AAL72315 | |
| GeneID | 1238011 13917039 | |
| KEGG | sfl:CP0010 | |
| eggNOG | NOG26011 | |
| HOGENOM | HOG000028458 | |
| KO | K13450 | |
| OMA | FTLYVKP | |
| OrthoDB | EOG6MM1JV | |
| EvolutionaryTrace | Q8VSP9 | |
| Proteomes | UP000001006 | |
| GO | GO:0005576 GO:0016829 GO:0000188 GO:0009405 | |
| InterPro | IPR003519 | |
| Pfam | PF03536 | |
| PRINTS | PR01342 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0075132 |
negative regulation by symbiont of host protein kinase-mediated signal transduction |
ECO:0000315 |
P |
Figure 1 indicates the ability of OspF to be specifically targeted to different scaffold complexes (such as yeast osmolarity scaffold Pbs2) where it can inhibit MAPK activity and prevent growth. |
complete | |||||
|
involved_in |
GO:0009405 |
pathogenesis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016829 |
lyase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Wei, P et al. (2012) Bacterial virulence proteins as tools to rewire kinase pathways in yeast and immune cells. Nature 488 384-8 PubMed GONUTS page