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SHIFL:OSPF
Contents
Species (Taxon ID) | Shigella flexneri. (623) | |
Gene Name(s) | ospF (synonyms: mkaD) | |
Protein Name(s) | Phosphothreonine lyase OspF
Effector protein OspF | |
External Links | ||
UniProt | Q8VSP9 | |
EMBL | AL391753 AF348706 AY206429 AY879342 AF386526 DQ362850 DQ362864 DQ362865 DQ362866 DQ362867 DQ362868 DQ362869 DQ362870 | |
RefSeq | NP_858143.1 WP_001121867.1 WP_010921598.1 YP_006960239.1 YP_009078261.1 | |
PDB | 3I0U | |
PDBsum | 3I0U | |
ProteinModelPortal | Q8VSP9 | |
SMR | Q8VSP9 | |
IntAct | Q8VSP9 | |
STRING | 198214.CP0010 | |
PRIDE | Q8VSP9 | |
EnsemblBacteria | AAL72315 | |
GeneID | 1238011 13917039 | |
KEGG | sfl:CP0010 | |
eggNOG | NOG26011 | |
HOGENOM | HOG000028458 | |
KO | K13450 | |
OMA | FTLYVKP | |
OrthoDB | EOG6MM1JV | |
EvolutionaryTrace | Q8VSP9 | |
Proteomes | UP000001006 | |
GO | GO:0005576 GO:0016829 GO:0000188 GO:0009405 | |
InterPro | IPR003519 | |
Pfam | PF03536 | |
PRINTS | PR01342 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0075132 |
negative regulation by symbiont of host protein kinase-mediated signal transduction |
ECO:0000315 |
P |
Figure 1 indicates the ability of OspF to be specifically targeted to different scaffold complexes (such as yeast osmolarity scaffold Pbs2) where it can inhibit MAPK activity and prevent growth. |
complete | |||||
involved_in |
GO:0009405 |
pathogenesis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0016829 |
lyase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Wei, P et al. (2012) Bacterial virulence proteins as tools to rewire kinase pathways in yeast and immune cells. Nature 488 384-8 PubMed GONUTS page