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SHIF2:D2AJK8
Contents
| Species (Taxon ID) | Shigella flexneri serotype X (strain 2002017). (591020) | |
| Gene Name(s) | spa32 (ECO:0000313 with EMBL:ADA76889.1) | |
| Protein Name(s) | Spa32, secreted by and component of the Mxi-Spa machinery (ECO:0000313 with EMBL:ADA76889.1) | |
| External Links | ||
| UniProt | D2AJK8 | |
| EMBL | CP001384 | |
| RefSeq | YP_005712043.1 | |
| PRIDE | D2AJK8 | |
| EnsemblBacteria | ADA76889 | |
| GeneID | 12284613 | |
| KEGG | sfe:SFxv_4994 | |
| PATRIC | 36752247 | |
| HOGENOM | HOG000061748 | |
| BioCyc | SFLE591020:GLK5-4892-MONOMER | |
| Proteomes | UP000001884 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0050714 |
positive regulation of protein secretion |
ECO:0000315 |
P |
Fig. 2.A "To characterize the role of spa32, we constructed a S. flexneri 5a strain, MJ321, in which the spa32 gene has been inactivated with a nonpolar cassette... The newly constructed strain was unable to bind CR and was thus white on agar plates at 37°C, suggesting that the spa32 gene product is required for the secretion of Ipa invasins. To test this, the proteins present in the culture supernatants of M90T (wild-type) and MJ321 strains induced by CR were analyzed by SDS-PAGE and immunoblotting. IpaA (70 kDa), IpaB (62 kDa), IpaC (41 kDa), and IpaD (39 kDa) were secreted by the wild-type strain but not by MJ321 (Fig. (Fig.2A).2A)." |
Missing: reference | |||||
| GO:0005576 |
extracellular region |
ECO:0000314 |
C |
Figure 3 shows that Spa32 is found in the supernatant of cell culture. |
Missing: reference | |||||
Notes
References
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