SALTY:SOPB

Species (Taxon ID)	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720). (99287)
Gene Name(s)	sopB (synonyms: sigD)
Protein Name(s)	Inositol phosphate phosphatase SopB Effector protein SopB
External Links
UniProt	O30916
EMBL	AF021817 AE006468 AF213335
RefSeq	NP_460064.1
PDB	4DID
PDBsum	4DID
MINT	MINT-157109
STRING	99287.STM1091
PaxDb	O30916
PRIDE	O30916
EnsemblBacteria	AAL20023
GeneID	1252609
KEGG	stm:STM1091
PATRIC	32380619
eggNOG	NOG29401
HOGENOM	HOG000028303
KO	K13085
OMA	CWNCKSG
OrthoDB	EOG67DPGJ
BioCyc	MetaCyc:MONOMER-15186 SENT99287:GCTI-1100-MONOMER
Proteomes	UP000001014
GO	GO:0005576 GO:0016791 GO:0009405
InterPro	IPR008108
Pfam	PF05925
PRINTS	PR01734

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0009279	cell outer membrane	PMID:20149234	ECO:0000314			C		Additional file 2: Comparison of the outer membrane proteins identified	complete
	GO:0006916	anti-apoptosis	PMID:15642738	ECO:0000315			P		Fig. 2. Infection with the sopB mutant caused a greater than 9-fold increase in apoptotic cells, whereas wild type S. enterica serovar Typhimurium increased the number of M30-reactive cells by only 5.0-fold. On the other side, the sopB complemented strain got lower number of apoptotic cells than sopB mutant strains group.	complete
	GO:0043154		PMID:15642738	ECO:0000315					Fig. 3. A statistically significant change in caspase-3 activity in cells infected with the sopB mutant strain compared with uninfected cells.Complementation of sopB mutant strain with pDE abrogated the ability of this strain to induce caspase-3 activity.	complete
	GO:0006260	DNA replication	PMID:21435037	ECO:0000315			P		Figure 9	complete CACAO 2627
part_of	GO:0020003	symbiont-containing vacuole	PMID:21435037	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0045859	regulation of protein kinase activity	PMID:21435037	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0042577	lipid phosphatase activity	PMID:21435037	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0071944	cell periphery	PMID:21435037	ECO:0000315	mutant phenotype evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0023057	negative regulation of signaling	PMID:21435037	ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_regulation_target:(UniProtKB:P60953)	Seeded From UniProt	complete
involved_in	GO:0030308	negative regulation of cell growth	PMID:21435037	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045740	positive regulation of DNA replication	PMID:21435037	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0016311	dephosphorylation	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0016791	P		Seeded From UniProt	complete
involved_in	GO:0016311	dephosphorylation	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0042577	P		Seeded From UniProt	complete
involved_in	GO:0009405	pathogenesis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008108	P		Seeded From UniProt	complete
enables	GO:0016791	phosphatase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR008108	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
involved_in	GO:0009405	pathogenesis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0843	P		Seeded From UniProt	complete
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