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SALTY:RIR3
Contents
| Species (Taxon ID) | Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720). (99287) | |
| Gene Name(s) | nrdE | |
| Protein Name(s) | Ribonucleoside-diphosphate reductase 2 subunit alpha
R1E protein Ribonucleotide reductase 2 | |
| External Links | ||
| UniProt | Q08698 | |
| EMBL | X73226 AE006468 | |
| PIR | S34271 | |
| RefSeq | NP_461733.1 WP_000246626.1 | |
| PDB | 1PEM 1PEO 1PEQ 1PEU 2BQ1 | |
| PDBsum | 1PEM 1PEO 1PEQ 1PEU 2BQ1 | |
| ProteinModelPortal | Q08698 | |
| SMR | Q08698 | |
| STRING | 99287.STM2807 | |
| PRIDE | Q08698 | |
| EnsemblBacteria | AAL21692 | |
| GeneID | 1254330 | |
| KEGG | stm:STM2807 | |
| PATRIC | 32384296 | |
| eggNOG | COG0209 | |
| HOGENOM | HOG000246165 | |
| KO | K00525 | |
| OMA | IYFYTVT | |
| OrthoDB | EOG6J48HC | |
| PhylomeDB | Q08698 | |
| BioCyc | MetaCyc:MONOMER-13835 SENT99287:GCTI-2824-MONOMER | |
| UniPathway | UPA00326 | |
| EvolutionaryTrace | Q08698 | |
| Proteomes | UP000001014 | |
| GO | GO:0005524 GO:0004748 GO:0006260 | |
| InterPro | IPR013346 IPR026459 IPR000788 IPR013509 IPR013554 IPR008926 | |
| Pfam | PF02867 PF00317 PF08343 | |
| PRINTS | PR01183 | |
| SUPFAM | SSF48168 | |
| TIGRFAMs | TIGR02506 TIGR04170 | |
| PROSITE | PS00089 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0005737 |
cytoplasm |
ECO:0000314 |
C |
complete | ||||||
| GO:0032564 |
dATP binding |
ECO:0000314 |
F |
"The reaction is strongly stimulated by dATP, which probably acts as a positive allosteric effector." |
complete | |||||
|
Contributes to |
GO:0004748 |
ribonucleoside-diphosphate reductase activity |
ECO:0000314 |
F |
With NrdF forms a class I ribonucleotide-diphosphate reductase. |
complete | ||||
|
involved_in |
GO:0009263 |
deoxyribonucleotide biosynthetic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10660 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005971 |
ribonucleoside-diphosphate reductase complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10660 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004748 |
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10660 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004748 |
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006260 |
DNA replication |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004748 |
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003824 |
catalytic activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006260 |
DNA replication |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0235 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008152 |
metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Jordan, A et al. (1994) A second class I ribonucleotide reductase in Enterobacteriaceae: characterization of the Salmonella typhimurium enzyme. Proc. Natl. Acad. Sci. U.S.A. 91 12892-6 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
