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SALTY:Q8ZQW9

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Species (Taxon ID) Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720). (99287)
Gene Name(s) pgm (ECO:0000313 with EMBL:AAL19642.1)
Protein Name(s) Phosphoglucomutase (ECO:0000313 with EMBL:AAL19642.1)
External Links
UniProt Q8ZQW9
EMBL AE006468
RefSeq NP_459683.1
PDB 2FUV
3NA5
3OLP
PDBsum 2FUV
3NA5
3OLP
ProteinModelPortal Q8ZQW9
SMR Q8ZQW9
STRING 99287.STM0698
PRIDE Q8ZQW9
EnsemblBacteria AAL19642
GeneID 1252218
KEGG stm:STM0698
PATRIC 32379755
HOGENOM HOG000268677
KO K01835
OMA YYARHDY
OrthoDB EOG6K13NV
PhylomeDB Q8ZQW9
BioCyc SENT99287:GCTI-701-MONOMER
EvolutionaryTrace Q8ZQW9
Proteomes UP000001014
GO GO:0000287
GO:0004614
GO:0005975
Gene3D 3.30.310.50
3.40.120.10
InterPro IPR005844
IPR016055
IPR005845
IPR005846
IPR005843
IPR016066
IPR005852
Pfam PF02878
PF02879
PF02880
PF00408
SUPFAM SSF53738
SSF55957
TIGRFAMs TIGR01132
PROSITE PS00710

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0004614

phosphoglucomutase activity

PMID:19589833[1]

ECO:0000315

F

Growth of SL1344 pgm in LB broth. Overnight cultures of SL1344 wild-type (▪) and SL1344 pgm (□) were inoculated into fresh pre-warmed LB and grown with shaking at 37 °C at 180 r.p.m (Fiugure 1). Susceptibility to antimicrobial peptides. Strains were exposed to melittin (5 μg ml−1) (a), cecropin P (3 μg ml−1) (b) or polymyxin B (10 μg ml−1) (c) and viable counts after 1 h (for melittin and polymyxin B) or 3 h (for cecropin P) expressed as the percentage of the count in PBS in the absence of these antimicrobial peptides (figure 3).

complete

GO:0004614

phosphoglucomutase activity

PMID:19589833[1]

ECO:0000315

F

see figure 1 and figure 3

complete

enables

GO:0000287

magnesium ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR016066

F

Seeded From UniProt

complete

enables

GO:0004614

phosphoglucomutase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005852

F

Seeded From UniProt

complete

involved_in

GO:0005975

carbohydrate metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005844
InterPro:IPR005845
InterPro:IPR005846
InterPro:IPR005852
InterPro:IPR016055

P

Seeded From UniProt

complete

enables

GO:0016868

intramolecular transferase activity, phosphotransferases

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005843
InterPro:IPR005844
InterPro:IPR005846
InterPro:IPR016055
InterPro:IPR036900

F

Seeded From UniProt

complete

involved_in

GO:0071704

organic substance metabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005843
InterPro:IPR036900

P

Seeded From UniProt

complete

enables

GO:0004614

phosphoglucomutase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:5.4.2.2

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0016853

isomerase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0413

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Paterson, GK et al. (2009) The enzyme phosphoglucomutase (Pgm) is required by Salmonella enterica serovar Typhimurium for O-antigen production, resistance to antimicrobial peptides and in vivo fitness. Microbiology (Reading, Engl.) 155 3403-10 PubMed GONUTS page