GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

SALTY:PRPE

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720). (99287)
Gene Name(s) prpE
Protein Name(s) Propionate--CoA ligase

Propionyl-CoA synthetase

External Links
UniProt P55912
EMBL U51879
AE006468
RefSeq NP_459366.1
WP_000010229.1
ProteinModelPortal P55912
STRING 99287.STM0371
PaxDb P55912
PRIDE P55912
EnsemblBacteria AAL19325
GeneID 1251890
KEGG stm:STM0371
PATRIC 32379063
eggNOG ENOG4108IQF
COG0365
HOGENOM HOG000229981
KO K01908
OMA LPVKHGS
PhylomeDB P55912
BioCyc MetaCyc:MONOMER-62
UniPathway UPA00946
Proteomes UP000001014
GO GO:0005524
GO:0050218
GO:0019629
InterPro IPR032387
IPR025110
IPR020845
IPR000873
IPR012694
Pfam PF16177
PF00501
PF13193
TIGRFAMs TIGR02316
PROSITE PS00455

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0050218

propionate-CoA ligase activity

PMID:27974467[1]

ECO:0000314

F

Organism: Salmonella enterica (Salmonella typhimurium). Paper's Protein Name: Propionyl-CoA synthetase (PrpE). UniProt's Protein Name: Propionate--CoA ligase. The control of Figure 6 shows that propionyl-CoA synthetase is involved with the activity of Propionate-CoA ligase.

complete
CACAO 12278

enables

GO:0003824

catalytic activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000873

F

Seeded From UniProt

complete

involved_in

GO:0019629

propionate catabolic process, 2-methylcitrate cycle

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012694

P

Seeded From UniProt

complete

enables

GO:0050218

propionate-CoA ligase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012694

F

Seeded From UniProt

complete

enables

GO:0050218

propionate-CoA ligase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:6.2.1.17

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

enables

GO:0016874

ligase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0436

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Han, X et al. (2017) Cyclic AMP Inhibits the Activity and Promotes the Acetylation of Acetyl-CoA Synthetase through Competitive Binding to the ATP/AMP Pocket. J. Biol. Chem. 292 1374-1384 PubMed GONUTS page