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SALTY:CYSK

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Species (Taxon ID) Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720). (99287)
Gene Name(s) cysK
Protein Name(s) Cysteine synthase A

CSase A O-acetylserine (thiol)-lyase A OAS-TL A O-acetylserine sulfhydrylase A

External Links
UniProt P0A1E3
EMBL M21450
AE006468
PIR B28181
RefSeq NP_461365.1
PDB 1D6S
1FCJ
1OAS
PDBsum 1D6S
1FCJ
1OAS
ProteinModelPortal P0A1E3
SMR P0A1E3
STRING 99287.STM2430
PaxDb P0A1E3
PRIDE P0A1E3
EnsemblBacteria AAL21324
GeneID 1253952
KEGG stm:STM2430
PATRIC 32383489
eggNOG COG0031
HOGENOM HOG000217394
KO K01738
OMA VKCRIGS
OrthoDB EOG6Q2SP8
PhylomeDB P0A1E3
BioCyc SENT99287:GCTI-2446-MONOMER
BRENDA 2.5.1.47
SABIO-RK P0A1E3
UniPathway UPA00136
EvolutionaryTrace P0A1E3
PRO PR:P0A1E3
Proteomes UP000001014
GO GO:0004124
GO:0016740
GO:0006535
InterPro IPR005856
IPR005859
IPR001216
IPR001926
Pfam PF00291
SUPFAM SSF53686
TIGRFAMs TIGR01139
TIGR01136
PROSITE PS00901

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0004124

cysteine synthase activity

PMID:3290198[1]

ECO:0000247

UniProtKB:P0ABK5


F

Results shows the S. typhimurium cysK DNA sequence 85% identical to that of E. coli, and the deduced amino acid sequences 96% identical (fig. 2). E. coli cysK gene has evidence of cysteine synthase acitivity.

complete

enables

GO:0080146

L-cysteine desulfhydrase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10192
PANTHER:PTN000034535

F

Seeded From UniProt

complete

enables

GO:0030170

pyridoxal phosphate binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10192
PANTHER:PTN000034104
UniProtKB:P35520
UniProtKB:P9WG59
UniProtKB:P9WP53
UniProtKB:P9WP55
UniProtKB:Q79FV4
WB:WBGene00013866

F

Seeded From UniProt

complete

involved_in

GO:0006535

cysteine biosynthetic process from serine

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10192
EcoGene:EG10193
PANTHER:PTN000034466
PomBase:SPBC36.04
SGD:S000003387
UniProtKB:P37887
UniProtKB:P9WP53
UniProtKB:P9WP55
WB:WBGene00007653
WB:WBGene00010759
WB:WBGene00019962

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000034104
SGD:S000003387
UniProtKB:P35520
WB:WBGene00013866

C

Seeded From UniProt

complete

enables

GO:0004124

cysteine synthase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10192
EcoGene:EG10193
PANTHER:PTN000034466
PomBase:SPBC36.04
TAIR:locus:2043964
TAIR:locus:2082837
TAIR:locus:2096454
TAIR:locus:2114804
TAIR:locus:2130419
UniProtKB:P37887
UniProtKB:P9WP55
UniProtKB:Q43725
UniProtKB:Q9SXS7
WB:WBGene00007653
WB:WBGene00010759
WB:WBGene00013866
WB:WBGene00019962

F

Seeded From UniProt

complete

enables

GO:0004124

cysteine synthase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005856
InterPro:IPR005859

F

Seeded From UniProt

complete

involved_in

GO:0006535

cysteine biosynthetic process from serine

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001216
InterPro:IPR005856
InterPro:IPR005859

P

Seeded From UniProt

complete

enables

GO:0004124

cysteine synthase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.5.1.47

F

Seeded From UniProt

complete

enables

GO:0003824

catalytic activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0021

F

Seeded From UniProt

complete

involved_in

GO:0008652

cellular amino acid biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0028

P

Seeded From UniProt

complete

involved_in

GO:0019344

cysteine biosynthetic process

GO_REF:0000037
GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0198
UniPathway:UPA00136

P

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

involved_in

GO:0008152

metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0021

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Byrne, CR et al. (1988) DNA sequences of the cysK regions of Salmonella typhimurium and Escherichia coli and linkage of the cysK regions to ptsH. J. Bacteriol. 170 3150-7 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page