SALTI:HLYE

Species (Taxon ID)	Salmonella typhi. (90370)
Gene Name(s)	hlyE (synonyms: clyA, sheA)
Protein Name(s)	Hemolysin E Cytotoxin ClyA Silent hemolysin SheA
External Links
UniProt	Q8Z727
EMBL	AJ313032 AJ313034 AL513382 AE014613
RefSeq	NP_455928.1 NP_805266.1
ProteinModelPortal	Q8Z727
SMR	Q8Z727
STRING	220341.STY1498
EnsemblBacteria	AAO69115 CAD01758
GeneID	1247887
KEGG	sty:STY1498
PATRIC	18540886
eggNOG	NOG72512
HOGENOM	HOG000051663
KO	K11139
OMA	KTVQNFF
OrthoDB	EOG6XWV0P
Proteomes	UP000000541 UP000002670
GO	GO:0020002 GO:0016021 GO:0042597 GO:0044179 GO:0009405
InterPro	IPR027018
Pfam	PF06109

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0019836	hemolysis by symbiont of host erythrocytes	PMID:12228306	ECO:0000315			P		Figure 5B shows hemolysis on blood agar containing horse erythrocytes by the Ty21A serovar, and none for a strain with an inactivated clyA gene.	complete CACAO 10545
	GO:0016021	integral component of membrane	PMID:18439098	ECO:0000315			C		Fig 1: the SARB collection shown to cause systemic infections in humans have SPI-18 and hlyE and express an active hemolysin revealed upon bacterial envelope destabilization.	complete CACAO 10725
involved_in	GO:0019836	hemolysis by symbiont of host erythrocytes	PMID:12228306	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0009405	pathogenesis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR027018	P		Seeded From UniProt	complete
involved_in	GO:0044179	hemolysis in other organism	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR027018	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
part_of	GO:0042597	periplasmic space	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0574 UniProtKB-SubCell:SL-0200	C		Seeded From UniProt	complete
part_of	GO:0020002	host cell plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1032 UniProtKB-SubCell:SL-0375	C		Seeded From UniProt	complete
involved_in	GO:0044179	hemolysis in other organism	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0354	P		Seeded From UniProt	complete
enables	GO:0090729	toxin activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0800	F		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964 UniProtKB-SubCell:SL-0243	C		Seeded From UniProt	complete
part_of	GO:0033644	host cell membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1043	C		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
involved_in	GO:0019835	cytolysis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0204	P		Seeded From UniProt	complete
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References

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