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SALT1:D0ZSD6

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Species (Taxon ID) Salmonella typhimurium (strain 14028s / SGSC 2262). (588858)
Gene Name(s) ybjZ (ECO:0000313 with EMBL:ACY87554.1) (synonyms: macB (ECO:0000256 with HAMAP-Rule:MF_01720))
Protein Name(s) Macrolide export ATP-binding/permease protein MacB (ECO:0000256 with HAMAP-Rule:MF_01720)
External Links
UniProt D0ZSD6
EMBL CP001363
RefSeq YP_005236650.1
ProteinModelPortal D0ZSD6
PRIDE D0ZSD6
EnsemblBacteria ACY87554
PATRIC 36733190
OMA ERTTHTL
BioCyc SENT588858:GJDZ-1060-MONOMER
Proteomes UP000002695
GO GO:0043190
GO:0042895
GO:0005524
GO:0016887
GO:0016820
GO:0046677
Gene3D 3.40.50.300
InterPro IPR003593
IPR003838
IPR003439
IPR017871
IPR017911
IPR025857
IPR027417
Pfam PF00005
PF02687
PF12704
SMART SM00382
SUPFAM SSF52540
PROSITE PS00211
PS50893
PS51267

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0043190

ATP-binding cassette (ABC) transporter complex

PMID:24169575[1]

ECO:0000315

C

In Figure 4, ΔmacAB mutants rapidly lost viability in the presence of 1 mM H2O2 as compared to wild-type Salmonella, suggesting MacAB is required for resistance to hydrogen peroxide in vitro.

complete
CACAO 9000

GO:0043190

ATP-binding cassette (ABC) transporter complex

PMID:24169575[1]

ECO:0000315

C

In Figure 5, wild-type Salmonella transcomplements hydrogen peroxide sensitivity of the macAB mutant

complete
CACAO 9001

involved_in

GO:0055085

transmembrane transport

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0015562

P

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003439
InterPro:IPR017871

F

Seeded From UniProt

complete

enables

GO:0015562

efflux transmembrane transporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017911

F

Seeded From UniProt

complete

involved_in

GO:0015893

drug transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR017911

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003838

C

Seeded From UniProt

complete

enables

GO:0016887

ATPase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR003439
InterPro:IPR017871

F

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0997

C

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

involved_in

GO:0046677

response to antibiotic

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0046

P

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-1003

C

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000040

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-SubCell:SL-0037

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000046410

C

Seeded From UniProt

complete

enables

GO:0042895

antibiotic transmembrane transporter activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000046410

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000400038

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000400038

F

Seeded From UniProt

complete

involved_in

GO:0042891

antibiotic transport

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000046410

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Bogomolnaya, LM et al. (2013) The ABC-type efflux pump MacAB protects Salmonella enterica serovar typhimurium from oxidative stress. MBio 4 e00630-13 PubMed GONUTS page