RICPR:TLCE

Species (Taxon ID)	Rickettsia prowazekii (strain Madrid E). (272947)
Gene Name(s)	tlcE (synonyms: tlc5)
Protein Name(s)	ADP,ATP carrier protein 5 ADP/ATP translocase 5
External Links
UniProt	O05962
EMBL	AJ235273 Y11778
PIR	G71633
RefSeq	NP_221091.1
ProteinModelPortal	O05962
TCDB	2.A.12.1.5
EnsemblBacteria	CAA15167
GeneID	883700
KEGG	rpr:RP739
PATRIC	17902337
eggNOG	COG3202
HOGENOM	HOG000238123
KO	K03301
OMA	MQHEREA
OrthoDB	EOG6BCSND
Proteomes	UP000002480
GO	GO:0016021 GO:0005886 GO:0005524 GO:0005471 GO:0015931
InterPro	IPR004667
PANTHER	PTHR31187:SF0
Pfam	PF03219
TIGRFAMs	TIGR00769

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0006810	transport	PMID:16923893	ECO:0000314			P		Figure 2B	complete CACAO 3810
	GO:0015931	nucleobase-containing compound transport	PMID:16923893	ECO:0000314			P		The Tlc5 gene was cloned into the pET-11a expression vector and introduced into the C41 strain of E. coli by electroporation. Using filtration uptake assays, it was shown, as seen in figure 2B, that Tlc5 was able to transport GTP and GDP with very similar maximum rates in the E. coli expression vector. It can also be seen in chart 3 that the only compounds that demonstrated substantial inhibition of GTP transport when present at a 10-fold excess were GTP and GDP.	complete CACAO 3984
involved_in	GO:0015931	nucleobase-containing compound transport	PMID:16923893	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0015866	ADP transport	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0005471	P		Seeded From UniProt	complete
involved_in	GO:0015867	ATP transport	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0005471	P		Seeded From UniProt	complete
enables	GO:0005471	ATP:ADP antiporter activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004667	F		Seeded From UniProt	complete
involved_in	GO:0006862	nucleotide transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004667	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004667	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
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References

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