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RAT:UT2

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Species (Taxon ID) Rattus norvegicus (Rat). (10116)
Gene Name(s) Slc14a2 (synonyms: Ut2)
Protein Name(s) Urea transporter 2

Solute carrier family 14 member 2 Urea transporter, kidney

External Links
UniProt Q62668
EMBL U09957
U77971
AF041788
AF042167
AF031642
RefSeq NP_001103740.1
NP_062220.2
NP_808877.2
UniGene Rn.10157
ProteinModelPortal Q62668
BioGrid 248522
IntAct Q62668
BindingDB Q62668
TCDB 1.A.28.1.1
PaxDb Q62668
PRIDE Q62668
GeneID 54302
KEGG rno:54302
CTD 8170
RGD 3689
eggNOG COG4413
HOGENOM HOG000168437
HOVERGEN HBG073255
InParanoid Q62668
KO K08716
PhylomeDB Q62668
NextBio 610950
PRO PR:Q62668
Proteomes UP000002494
Genevestigator Q62668
GO GO:0016324
GO:0016021
GO:0015204
GO:0009414
GO:0015840
Gene3D 1.10.3430.10
InterPro IPR029020
IPR004937
PANTHER PTHR10464
Pfam PF03253

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0015840

urea transport

PMID:23552862[1]

ECO:0000315

P

The research and experiments done provide necessary information about urea transport

complete
CACAO 10601

involved_in

GO:0015840

urea transport

PMID:10215321[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0015840

urea transport

PMID:11267655[3]

ECO:0000303

author statement without traceable support used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0015204

urea transmembrane transporter activity

PMID:10215321[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0015204

urea transmembrane transporter activity

PMID:11267655[3]

ECO:0000303

author statement without traceable support used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0009414

response to water deprivation

PMID:11267655[3]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0071918

urea transmembrane transport

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1351653
MGI:MGI:1351654
PANTHER:PTN002573341
RGD:3688
RGD:3689
UniProtKB:Q13336
UniProtKB:Q5QF96

P

Seeded From UniProt

complete

involved_in

GO:0015840

urea transport

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1351653
MGI:MGI:1351654
PANTHER:PTN002573341
RGD:3688
RGD:3689
UniProtKB:Q13336
UniProtKB:Q5QF96
ZFIN:ZDB-GENE-030131-4833

P

Seeded From UniProt

complete

enables

GO:0015265

urea channel activity

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001627166
UniProtKB:Q13336
UniProtKB:Q5QF96

F

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:21873635[4]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001627166
UniProtKB:Q13336
UniProtKB:Q5QF96

C

Seeded From UniProt

complete

enables

GO:0015204

urea transmembrane transporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004937

F

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004937

C

Seeded From UniProt

complete

involved_in

GO:0071918

urea transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004937

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0016324

apical plasma membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0015

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Geyer, RR et al. (2013) Movement of NH₃ through the human urea transporter B: a new gas channel. Am. J. Physiol. Renal Physiol. 304 F1447-57 PubMed GONUTS page
  2. 2.0 2.1 Karakashian, A et al. (1999) Cloning and characterization of two new isoforms of the rat kidney urea transporter: UT-A3 and UT-A4. J. Am. Soc. Nephrol. 10 230-7 PubMed GONUTS page
  3. 3.0 3.1 3.2 Nakayama, Y et al. (2001) Cloning of the rat Slc14a2 gene and genomic organization of the UT-A urea transporter. Biochim. Biophys. Acta 1518 19-26 PubMed GONUTS page
  4. 4.0 4.1 4.2 4.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page