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RAT:SLIT3

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Species (Taxon ID) Rattus norvegicus (Rat). (10116)
Gene Name(s) Slit3 (synonyms: Megf5)
Protein Name(s) Slit homolog 3 protein

Slit-3 Multiple epidermal growth factor-like domains protein 5 Multiple EGF-like domains protein 5

External Links
UniProt O88280
EMBL AB011531
PIR T13953
RefSeq NP_112611.1
UniGene Rn.12298
ProteinModelPortal O88280
SMR O88280
IntAct O88280
STRING 10116.ENSRNOP00000009714
PaxDb O88280
PRIDE O88280
GeneID 83467
KEGG rno:83467
UCSC RGD:69311
CTD 6586
RGD 69311
eggNOG COG4886
HOGENOM HOG000116120
HOVERGEN HBG057959
InParanoid O88280
KO K06850
PhylomeDB O88280
NextBio 615863
PRO PR:O88280
Proteomes UP000002494
Genevestigator O88280
GO GO:0005576
GO:0016020
GO:0005509
GO:0007420
GO:0030154
GO:0021510
Gene3D 2.60.120.200
InterPro IPR013320
IPR000483
IPR006207
IPR000742
IPR001881
IPR013032
IPR000152
IPR018097
IPR009030
IPR001791
IPR001611
IPR003591
IPR000372
Pfam PF00008
PF12661
PF02210
PF13855
PF01463
PF01462
SMART SM00041
SM00181
SM00179
SM00282
SM00369
SM00082
SM00013
SUPFAM SSF49899
SSF57184
PROSITE PS01185
PS01225
PS00022
PS01186
PS50026
PS01187
PS50025
PS51450

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0005624

membrane fraction

ECO:0000315

C

Source: RGD

Missing: reference

GO:0005739

mitochondrion

ECO:0000315

C

Source: RGD

Missing: reference

GO:0007420

brain development

PMID:11754167[1]

ECO:0000270

P

complete

GO:0021510

spinal cord development

PMID:10102268[2]

ECO:0000270

P

complete

GO:0003674

molecular function

ECO:0000307

F

Missing: reference

involved_in

GO:0021510

spinal cord development

PMID:10102268[2]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

PMID:11443047[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0007420

brain development

PMID:11754167[1]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

colocalizes_with

GO:0005739

mitochondrion

PMID:11443047[3]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003674

molecular_function

GO_REF:0000015

ECO:0000307

no biological data found used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0005509

calcium ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001881
InterPro:IPR018097

F

Seeded From UniProt

complete

involved_in

GO:0030154

cell differentiation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0221

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

involved_in

GO:0007399

nervous system development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0524

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Marillat, V et al. (2002) Spatiotemporal expression patterns of slit and robo genes in the rat brain. J. Comp. Neurol. 442 130-55 PubMed GONUTS page
  2. 2.0 2.1 Brose, K et al. (1999) Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance. Cell 96 795-806 PubMed GONUTS page
  3. 3.0 3.1 Little, MH et al. (2001) Dual trafficking of Slit3 to mitochondria and cell surface demonstrates novel localization for Slit protein. Am. J. Physiol., Cell Physiol. 281 C486-95 PubMed GONUTS page