RAT:SHAN2

Species (Taxon ID)	Rattus norvegicus (Rat). (10116)
Gene Name(s)	Shank2 (synonyms: Cortbp1)
Protein Name(s)	SH3 and multiple ankyrin repeat domains protein 2 Shank2 Cortactin-binding protein 1 CortBP1 GKAP/SAPAP-interacting protein Proline-rich synapse-associated protein 1 ProSAP1 SPANK-3
External Links
UniProt	Q9QX74
EMBL	AF060116 AJ249562 AJ131899 AJ131899 AJ131899 AY298755 AF141903 AF159048
PIR	T14272
RefSeq	NP_001004133.1 NP_597684.1 NP_597685.1 NP_958738.1
UniGene	Rn.14545
ProteinModelPortal	Q9QX74
SMR	Q9QX74
BioGrid	251104
IntAct	Q9QX74
MINT	MINT-143507
PhosphoSite	Q9QX74
PaxDb	Q9QX74
PRIDE	Q9QX74
GeneID	171093
KEGG	rno:171093
UCSC	RGD:628772
CTD	22941
RGD	628772
eggNOG	COG0666
HOVERGEN	HBG054027
InParanoid	Q9QX74
KO	K15009
NextBio	621752
PRO	PR:Q9QX74
Proteomes	UP000002494
Genevestigator	Q9QX74
GO	GO:0016324 GO:0031526 GO:0030054 GO:0060170 GO:0005737 GO:0043197 GO:0030426 GO:0043005 GO:0043025 GO:0001917 GO:0001750 GO:0005886 GO:0014069 GO:0045211 GO:0035255 GO:0008022 GO:0017124 GO:0030534 GO:0007420 GO:0035640 GO:0007612 GO:0060292 GO:0060291 GO:0007613 GO:0007584 GO:0035176 GO:0007416 GO:0071625
Gene3D	1.10.150.50 2.30.42.10
InterPro	IPR001478 IPR001660 IPR013761 IPR021129 IPR011511 IPR001452
Pfam	PF00595 PF00536 PF07653
SMART	SM00228 SM00454 SM00326
SUPFAM	SSF47769 SSF50044 SSF50156
PROSITE	PS50106 PS50105 PS50002

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0060170	cilium membrane	PMID:18596612^[1]	ECO:0000314			C		Subcellular fractionation, Figure 4 A and B showed from cilia fraction Shank2 located at the cilia membrane	complete CACAO 3196
involved_in	GO:0099562	maintenance of postsynaptic density structure	GO_REF:0000036	ECO:0000305	curator inference used in manual assertion	GO:0005515,GO:0014069	P		Seeded From UniProt	complete
enables	GO:0098919	structural constituent of postsynaptic density	GO_REF:0000036	ECO:0000305	curator inference used in manual assertion	GO:0005515,GO:0014069	F		Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	PMID:10414979^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0002609)	Seeded From UniProt	complete
part_of	GO:0060170	ciliary membrane	PMID:18596612^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0071625	vocalization behavior	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q80Z38	P		Seeded From UniProt	complete
involved_in	GO:0060292	long-term synaptic depression	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q80Z38	P		Seeded From UniProt	complete
involved_in	GO:0060291	long-term synaptic potentiation	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q80Z38	P		Seeded From UniProt	complete
part_of	GO:0060170	ciliary membrane	PMID:18596612^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
colocalizes_with	GO:0045211	postsynaptic membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q80Z38	C		Seeded From UniProt	complete
part_of	GO:0043197	dendritic spine	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q80Z38	C		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q80Z38	C	part_of:(CL:0002608)	Seeded From UniProt	complete
involved_in	GO:0035640	exploration behavior	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q80Z38	P		Seeded From UniProt	complete
enables	GO:0035255	ionotropic glutamate receptor binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q80Z38	F		Seeded From UniProt	complete
involved_in	GO:0035176	social behavior	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q80Z38	P		Seeded From UniProt	complete
involved_in	GO:0030534	adult behavior	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q80Z38	P		Seeded From UniProt	complete
colocalizes_with	GO:0008328	ionotropic glutamate receptor complex	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q80Z38	C		Seeded From UniProt	complete
involved_in	GO:0007613	memory	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q80Z38	P		Seeded From UniProt	complete
involved_in	GO:0007612	learning	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q80Z38	P		Seeded From UniProt	complete
involved_in	GO:0007416	synapse assembly	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q80Z38	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q80Z38	C		Seeded From UniProt	complete
colocalizes_with	GO:0005883	neurofilament	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q80Z38	C		Seeded From UniProt	complete
part_of	GO:0001917	photoreceptor inner segment	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q80Z38	C		Seeded From UniProt	complete
part_of	GO:0001750	photoreceptor outer segment	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q80Z38	C		Seeded From UniProt	complete
part_of	GO:0016324	apical plasma membrane	PMID:17244609^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	PMID:21217644^[4]	ECO:0006063	over expression analysis evidence used in manual assertion		C	part_of:(UBERON:0002421)	Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	PMID:21217644^[4]	ECO:0006052	RNAi evidence used in manual assertion		C	part_of:(UBERON:0002421)	Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	PMID:21217644^[4]	ECO:0006003	electron microscopy evidence used in manual assertion		C	part_of:(UBERON:0002421)	Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	PMID:10414979^[2]	ECO:0006003	electron microscopy evidence used in manual assertion		C	part_of:(UBERON:0002421)	Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	PMID:21217644^[4]	ECO:0005589	confocal microscopy evidence used in manual assertion		C	part_of:(UBERON:0002421)	Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	PMID:10414979^[2]	ECO:0005589	confocal microscopy evidence used in manual assertion		C	part_of:(UBERON:0002421)	Seeded From UniProt	complete
enables	GO:0098919	structural constituent of postsynaptic density	PMID:21217644^[4]	ECO:0006063	over expression analysis evidence used in manual assertion		F	occurs_in:(GO:0098978) occurs_in:(UBERON:0002421)	Seeded From UniProt	complete
enables	GO:0098919	structural constituent of postsynaptic density	PMID:21217644^[4]	ECO:0006052	RNAi evidence used in manual assertion		F	occurs_in:(GO:0098978) occurs_in:(UBERON:0002421)	Seeded From UniProt	complete
enables	GO:0098919	structural constituent of postsynaptic density	PMID:21217644^[4]	ECO:0006003	electron microscopy evidence used in manual assertion		F	occurs_in:(GO:0098978) occurs_in:(UBERON:0002421)	Seeded From UniProt	complete
enables	GO:0098919	structural constituent of postsynaptic density	PMID:21217644^[4]	ECO:0005589	confocal microscopy evidence used in manual assertion		F	occurs_in:(GO:0098978) occurs_in:(UBERON:0002421)	Seeded From UniProt	complete
part_of	GO:0098686	hippocampal mossy fiber to CA3 synapse	PMID:10414979^[2]	ECO:0006003	electron microscopy evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0098686	hippocampal mossy fiber to CA3 synapse	PMID:10414979^[2]	ECO:0005589	confocal microscopy evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0050807	regulation of synapse organization	PMID:21217644^[4]	ECO:0006063	over expression analysis evidence used in manual assertion		P	occurs_in:(GO:0098978) occurs_in:(UBERON:0002421)	Seeded From UniProt	complete
involved_in	GO:0050807	regulation of synapse organization	PMID:21217644^[4]	ECO:0006052	RNAi evidence used in manual assertion		P	occurs_in:(GO:0098978) occurs_in:(UBERON:0002421)	Seeded From UniProt	complete
involved_in	GO:0050807	regulation of synapse organization	PMID:21217644^[4]	ECO:0006003	electron microscopy evidence used in manual assertion		P	occurs_in:(GO:0098978) occurs_in:(UBERON:0002421)	Seeded From UniProt	complete
involved_in	GO:0050807	regulation of synapse organization	PMID:21217644^[4]	ECO:0005589	confocal microscopy evidence used in manual assertion		P	occurs_in:(GO:0098978) occurs_in:(UBERON:0002421)	Seeded From UniProt	complete
part_of	GO:0032279	asymmetric synapse	PMID:10414979^[2]	ECO:0006003	electron microscopy evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0032279	asymmetric synapse	PMID:10414979^[2]	ECO:0005589	confocal microscopy evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	PMID:10414979^[2]	ECO:0006003	electron microscopy evidence used in manual assertion		C	part_of:(GO:0098978) part_of:(UBERON:0002421)	Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	PMID:10414979^[2]	ECO:0006003	electron microscopy evidence used in manual assertion		C	part_of:(GO:0032279) part_of:(GO:0098686)	Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	PMID:10414979^[2]	ECO:0005589	confocal microscopy evidence used in manual assertion		C	part_of:(GO:0098978) part_of:(UBERON:0002421)	Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	PMID:10414979^[2]	ECO:0005589	confocal microscopy evidence used in manual assertion		C	part_of:(GO:0032279) part_of:(GO:0098686)	Seeded From UniProt	complete
part_of	GO:0043025	neuronal cell body	PMID:10958799^[5]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0031526	brush border membrane	PMID:15917299^[6]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0030426	growth cone	PMID:10958799^[5]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0017124	SH3 domain binding	PMID:15014124^[7]	ECO:0000353	physical interaction evidence used in manual assertion	RGD:70941	F		Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	PMID:16439662^[8]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	PMID:15014124^[7]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0008022	protein C-terminus binding	PMID:15917299^[6]	ECO:0000353	physical interaction evidence used in manual assertion	RGD:3708	F		Seeded From UniProt	complete
enables	GO:0008022	protein C-terminus binding	PMID:10958799^[5]	ECO:0000353	physical interaction evidence used in manual assertion	RGD:620768	F		Seeded From UniProt	complete
involved_in	GO:0007584	response to nutrient	PMID:15917299^[6]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007420	brain development	PMID:10964907^[9]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:2000463	positive regulation of excitatory postsynaptic potential	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 MGI:MGI:3613677 PANTHER:PTN001191880	P		Seeded From UniProt	complete
involved_in	GO:2000311	regulation of AMPA receptor activity	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:3613677 PANTHER:PTN001191880	P		Seeded From UniProt	complete
involved_in	GO:0097107	postsynaptic density assembly	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 PANTHER:PTN001191880	P		Seeded From UniProt	complete
involved_in	GO:0060999	positive regulation of dendritic spine development	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 PANTHER:PTN001191880 RGD:621011	P		Seeded From UniProt	complete
involved_in	GO:0060997	dendritic spine morphogenesis	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 MGI:MGI:3613677 PANTHER:PTN001191880	P		Seeded From UniProt	complete
involved_in	GO:0060291	long-term synaptic potentiation	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 MGI:MGI:2671987 PANTHER:PTN001191880	P		Seeded From UniProt	complete
involved_in	GO:0051968	positive regulation of synaptic transmission, glutamatergic	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 MGI:MGI:2671987 PANTHER:PTN001191880	P		Seeded From UniProt	complete
involved_in	GO:0051124	synaptic growth at neuromuscular junction	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0040752 PANTHER:PTN001191880	P		Seeded From UniProt	complete
involved_in	GO:0048854	brain morphogenesis	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 PANTHER:PTN001191880 ZFIN:ZDB-GENE-060503-369	P		Seeded From UniProt	complete
colocalizes_with	GO:0045211	postsynaptic membrane	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2671987 MGI:MGI:3613677 PANTHER:PTN001191880 RGD:621011	C		Seeded From UniProt	complete
part_of	GO:0044309	neuron spine	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 PANTHER:PTN001191880	C		Seeded From UniProt	complete
part_of	GO:0043197	dendritic spine	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2671987 MGI:MGI:3613677 PANTHER:PTN001191880 RGD:621011	C		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 MGI:MGI:2671987 MGI:MGI:3613677 PANTHER:PTN001191880	C		Seeded From UniProt	complete
enables	GO:0035255	ionotropic glutamate receptor binding	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 MGI:MGI:2671987 MGI:MGI:3613677 PANTHER:PTN001191878 RGD:621011	F		Seeded From UniProt	complete
part_of	GO:0030425	dendrite	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:3613677 PANTHER:PTN001191880	C		Seeded From UniProt	complete
enables	GO:0030160	GKAP/Homer scaffold activity	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:3613677 PANTHER:PTN001191878 RGD:621011 RGD:69264	F		Seeded From UniProt	complete
enables	GO:0030159	receptor signaling complex scaffold activity	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001191878 RGD:621011	F		Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0040752 MGI:MGI:3613677 PANTHER:PTN001191880 RGD:628772 RGD:69264	C		Seeded From UniProt	complete
colocalizes_with	GO:0008328	ionotropic glutamate receptor complex	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2671987 MGI:MGI:3613677 PANTHER:PTN001191878	C		Seeded From UniProt	complete
involved_in	GO:0007416	synapse assembly	PMID:21873635^[10]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 MGI:MGI:2671987 PANTHER:PTN001191880	P		Seeded From UniProt	complete
part_of	GO:0048786	presynaptic active zone	PMID:21119615^[11]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
part_of	GO:0045202	synapse	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0770 UniProtKB-SubCell:SL-0258	C		Seeded From UniProt	complete
part_of	GO:0045211	postsynaptic membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0628	C		Seeded From UniProt	complete
part_of	GO:0042995	cell projection	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0966	C		Seeded From UniProt	complete
part_of	GO:0030054	cell junction	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0965	C		Seeded From UniProt	complete
enables	GO:0017124	SH3 domain binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0729	F		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003	C		Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0297	C		Seeded From UniProt	complete
part_of	GO:0043197	dendritic spine	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0284	C		Seeded From UniProt	complete
part_of	GO:0016324	apical plasma membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0015	C		Seeded From UniProt	complete
part_of	GO:0030426	growth cone	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0288	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 Saavedra, MV et al. (2008) Scaffolding proteins in highly purified rat olfactory cilia membranes. Neuroreport 19 1123-6 PubMed GONUTS page
↑ ^2.00 ^2.01 ^2.02 ^2.03 ^2.04 ^2.05 ^2.06 ^2.07 ^2.08 ^2.09 ^2.10 Boeckers, TM et al. (1999) Proline-rich synapse-associated protein-1/cortactin binding protein 1 (ProSAP1/CortBP1) is a PDZ-domain protein highly enriched in the postsynaptic density. J. Neurosci. 19 6506-18 PubMed GONUTS page
↑ Lee, JH et al. (2007) Dynamic regulation of cystic fibrosis transmembrane conductance regulator by competitive interactions of molecular adaptors. J. Biol. Chem. 282 10414-22 PubMed GONUTS page
↑ ^4.00 ^4.01 ^4.02 ^4.03 ^4.04 ^4.05 ^4.06 ^4.07 ^4.08 ^4.09 ^4.10 ^4.11 Grabrucker, AM et al. (2011) Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation. EMBO J. 30 569-81 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 Tobaben, S et al. (2000) The G protein-coupled receptor CL1 interacts directly with proteins of the Shank family. J. Biol. Chem. 275 36204-10 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 McWilliams, RR et al. (2005) Shank2E binds NaP(i) cotransporter at the apical membrane of proximal tubule cells. Am. J. Physiol., Cell Physiol. 289 C1042-51 PubMed GONUTS page
↑ ^7.0 ^7.1 Qualmann, B et al. (2004) Linkage of the actin cytoskeleton to the postsynaptic density via direct interactions of Abp1 with the ProSAP/Shank family. J. Neurosci. 24 2481-95 PubMed GONUTS page
↑ Baron, MK et al. (2006) An architectural framework that may lie at the core of the postsynaptic density. Science 311 531-5 PubMed GONUTS page
↑ Kreienkamp, HJ et al. (2000) The calcium-independent receptor for alpha-latrotoxin from human and rodent brains interacts with members of the ProSAP/SSTRIP/Shank family of multidomain proteins. J. Biol. Chem. 275 32387-90 PubMed GONUTS page
↑ ^10.00 ^10.01 ^10.02 ^10.03 ^10.04 ^10.05 ^10.06 ^10.07 ^10.08 ^10.09 ^10.10 ^10.11 ^10.12 ^10.13 ^10.14 ^10.15 ^10.16 ^10.17 ^10.18 ^10.19 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Yang, J et al. (2011) DGKι regulates presynaptic release during mGluR-dependent LTD. EMBO J. 30 165-80 PubMed GONUTS page

[PMID:18596612-1] 1.0 ^1.1 ^1.2 Saavedra, MV et al. (2008) Scaffolding proteins in highly purified rat olfactory cilia membranes. Neuroreport 19 1123-6 PubMed GONUTS page

[PMID:10414979-2] 2.00 ^2.01 ^2.02 ^2.03 ^2.04 ^2.05 ^2.06 ^2.07 ^2.08 ^2.09 ^2.10 Boeckers, TM et al. (1999) Proline-rich synapse-associated protein-1/cortactin binding protein 1 (ProSAP1/CortBP1) is a PDZ-domain protein highly enriched in the postsynaptic density. J. Neurosci. 19 6506-18 PubMed GONUTS page

[PMID:17244609-3] Lee, JH et al. (2007) Dynamic regulation of cystic fibrosis transmembrane conductance regulator by competitive interactions of molecular adaptors. J. Biol. Chem. 282 10414-22 PubMed GONUTS page

[PMID:21217644-4] 4.00 ^4.01 ^4.02 ^4.03 ^4.04 ^4.05 ^4.06 ^4.07 ^4.08 ^4.09 ^4.10 ^4.11 Grabrucker, AM et al. (2011) Concerted action of zinc and ProSAP/Shank in synaptogenesis and synapse maturation. EMBO J. 30 569-81 PubMed GONUTS page

[PMID:10958799-5] 5.0 ^5.1 ^5.2 Tobaben, S et al. (2000) The G protein-coupled receptor CL1 interacts directly with proteins of the Shank family. J. Biol. Chem. 275 36204-10 PubMed GONUTS page

[PMID:15917299-6] 6.0 ^6.1 ^6.2 McWilliams, RR et al. (2005) Shank2E binds NaP(i) cotransporter at the apical membrane of proximal tubule cells. Am. J. Physiol., Cell Physiol. 289 C1042-51 PubMed GONUTS page

[PMID:15014124-7] 7.0 ^7.1 Qualmann, B et al. (2004) Linkage of the actin cytoskeleton to the postsynaptic density via direct interactions of Abp1 with the ProSAP/Shank family. J. Neurosci. 24 2481-95 PubMed GONUTS page

[PMID:16439662-8] Baron, MK et al. (2006) An architectural framework that may lie at the core of the postsynaptic density. Science 311 531-5 PubMed GONUTS page

[PMID:10964907-9] Kreienkamp, HJ et al. (2000) The calcium-independent receptor for alpha-latrotoxin from human and rodent brains interacts with members of the ProSAP/SSTRIP/Shank family of multidomain proteins. J. Biol. Chem. 275 32387-90 PubMed GONUTS page

[PMID:21873635-10] 10.00 ^10.01 ^10.02 ^10.03 ^10.04 ^10.05 ^10.06 ^10.07 ^10.08 ^10.09 ^10.10 ^10.11 ^10.12 ^10.13 ^10.14 ^10.15 ^10.16 ^10.17 ^10.18 ^10.19 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21119615-11] Yang, J et al. (2011) DGKι regulates presynaptic release during mGluR-dependent LTD. EMBO J. 30 165-80 PubMed GONUTS page

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RAT:SHAN2

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