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RAT:SECR
Contents
Species (Taxon ID) | Rattus norvegicus (Rat). (10116) | |
Gene Name(s) | Sct | |
Protein Name(s) | Secretin | |
External Links | ||
UniProt | P11384 | |
EMBL | M31495 M64033 M63984 | |
PIR | A40886 | |
RefSeq | NP_073161.1 XP_006230580.1 | |
UniGene | Rn.9919 | |
STRING | 10116.ENSRNOP00000024094 | |
Ensembl | ENSRNOT00000024094 | |
GeneID | 24769 | |
KEGG | rno:24769 | |
UCSC | RGD:3643 | |
CTD | 6343 | |
RGD | 3643 | |
eggNOG | NOG329190 | |
GeneTree | ENSGT00390000002624 | |
HOGENOM | HOG000133017 | |
HOVERGEN | HBG017786 | |
InParanoid | P11384 | |
KO | K05263 | |
OMA | MPILQAW | |
OrthoDB | EOG77DJ88 | |
PhylomeDB | P11384 | |
TreeFam | TF338215 | |
Reactome | REACT_235881 REACT_246814 | |
NextBio | 604336 | |
PRO | PR:P11384 | |
Proteomes | UP000002494 | |
Genevestigator | P11384 | |
GO | GO:0005576 GO:0021542 GO:0043524 GO:0097150 GO:0008542 | |
InterPro | IPR000532 IPR015675 | |
PANTHER | PTHR17378 | |
Pfam | PF00123 | |
SMART | SM00070 | |
PROSITE | PS00260 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
involved_in |
GO:1903640 |
negative regulation of gastrin-induced gastric acid secretion |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0090274 |
positive regulation of somatostatin secretion |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0090187 |
positive regulation of pancreatic juice secretion |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0048566 |
embryonic digestive tract development |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0047485 |
protein N-terminus binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
RGD:621342 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0043950 |
positive regulation of cAMP-mediated signaling |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007420 |
brain development |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005615 |
extracellular space |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0005102 |
signaling receptor binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
RGD:621342 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:1903640 |
negative regulation of gastrin-induced gastric acid secretion |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001048642 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0090274 |
positive regulation of somatostatin secretion |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001048642 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0090187 |
positive regulation of pancreatic juice secretion |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001048642 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007420 |
brain development |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001048642 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005615 |
extracellular space |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001048642 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0005102 |
signaling receptor binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001048642 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005179 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005179 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0001664 |
G protein-coupled receptor binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P09683 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0005179 |
hormone activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005576 |
extracellular region |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0005179 |
hormone activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Solomon, TE et al. (2001) Different actions of secretin and Gly-extended secretin predict secretin receptor subtypes. Am. J. Physiol. Gastrointest. Liver Physiol. 280 G88-94 PubMed GONUTS page
- ↑ Kopin, AS et al. (1991) The secretin gene: evolutionary history, alternative splicing, and developmental regulation. Proc. Natl. Acad. Sci. U.S.A. 88 5335-9 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Dong, M et al. (2002) Interaction among four residues distributed through the secretin pharmacophore and a focused region of the secretin receptor amino terminus. Mol. Endocrinol. 16 2490-501 PubMed GONUTS page
- ↑ Tay, J et al. (2004) Age-related and regional differences in secretin and secretin receptor mRNA levels in the rat brain. Neurosci. Lett. 366 176-81 PubMed GONUTS page
- ↑ Murthy, SN & Ganiban, G () Effect of the secretin family of peptides on gastric emptying and small intestinal transit in rats. Peptides 9 583-8 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 6.3 6.4 6.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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