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RAT:P2RY4

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Species (Taxon ID) Rattus norvegicus (Rat). (10116)
Gene Name(s) P2ry4 (synonyms: P2y4)
Protein Name(s) P2Y purinoceptor 4

P2Y4

External Links
UniProt O35811
EMBL Y14705
Y11433
RefSeq NP_113868.1
XP_006257155.1
XP_006257156.1
XP_006257157.1
XP_008771491.1
XP_008771492.1
UniGene Rn.30068
ProteinModelPortal O35811
STRING 10116.ENSRNOP00000039027
BindingDB O35811
ChEMBL CHEMBL2124
GuidetoPHARMACOLOGY 325
PhosphoSite O35811
PaxDb O35811
PRIDE O35811
Ensembl ENSRNOT00000045907
GeneID 63843
KEGG rno:63843
UCSC RGD:61798
CTD 5030
RGD 61798
eggNOG NOG270952
GeneTree ENSGT00760000118784
HOGENOM HOG000231307
HOVERGEN HBG101120
InParanoid O35811
KO K04271
OMA YMFHLAL
OrthoDB EOG7QNVM4
PhylomeDB O35811
TreeFam TF350009
Reactome REACT_233455
REACT_257071
NextBio 612438
PRO PR:O35811
Proteomes UP000002494
Genevestigator O35811
GO GO:0016324
GO:0016323
GO:0016021
GO:0005524
GO:0045028
GO:0045030
GO:0030321
InterPro IPR000276
IPR017452
IPR000018
PANTHER PTHR24231:SF21
Pfam PF00001
PRINTS PR00237
PR01066
PROSITE PS00237
PS50262

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:2000300

regulation of synaptic vesicle exocytosis

PMID:16000618[1]

ECO:0006062

wide-field fluorescence microscopy evidence used in manual assertion

P

  • occurs_in:(GO:0098978)
  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0002421)

Seeded From UniProt

complete

involved_in

GO:2000300

regulation of synaptic vesicle exocytosis

PMID:16000618[1]

ECO:0006054

pharmacological assay evidence used in manual assertion

P

  • occurs_in:(GO:0098978)
  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0002421)

Seeded From UniProt

complete

involved_in

GO:2000300

regulation of synaptic vesicle exocytosis

PMID:16000618[1]

ECO:0006042

cell fractionation evidence used in manual assertion

P

  • occurs_in:(GO:0098978)
  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0002421)

Seeded From UniProt

complete

involved_in

GO:2000300

regulation of synaptic vesicle exocytosis

PMID:16000618[1]

ECO:0000279

western blot evidence used in manual assertion

P

  • occurs_in:(GO:0098978)
  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0002421)

Seeded From UniProt

complete

involved_in

GO:0099509

regulation of presynaptic cytosolic calcium ion concentration

PMID:16000618[1]

ECO:0006062

wide-field fluorescence microscopy evidence used in manual assertion

P

  • occurs_in:(GO:0098978)
  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0002421)

Seeded From UniProt

complete

involved_in

GO:0099509

regulation of presynaptic cytosolic calcium ion concentration

PMID:16000618[1]

ECO:0006054

pharmacological assay evidence used in manual assertion

P

  • occurs_in:(GO:0098978)
  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0002421)

Seeded From UniProt

complete

involved_in

GO:0099509

regulation of presynaptic cytosolic calcium ion concentration

PMID:16000618[1]

ECO:0006042

cell fractionation evidence used in manual assertion

P

  • occurs_in:(GO:0098978)
  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0002421)

Seeded From UniProt

complete

involved_in

GO:0099509

regulation of presynaptic cytosolic calcium ion concentration

PMID:16000618[1]

ECO:0000279

western blot evidence used in manual assertion

P

  • occurs_in:(GO:0098978)
  • occurs_in:(UBERON:0000061)
  • occurs_in:(UBERON:0002421)

Seeded From UniProt

complete

part_of

GO:0099059

integral component of presynaptic active zone membrane

PMID:16000618[1]

ECO:0006042

cell fractionation evidence used in manual assertion

C

part_of:(UBERON:0002421)

Seeded From UniProt

complete

part_of

GO:0099059

integral component of presynaptic active zone membrane

PMID:16000618[1]

ECO:0000279

western blot evidence used in manual assertion

C

part_of:(UBERON:0002421)

Seeded From UniProt

complete

part_of

GO:0098978

glutamatergic synapse

PMID:16000618[1]

ECO:0006062

wide-field fluorescence microscopy evidence used in manual assertion

C

part_of:(UBERON:0002421)

Seeded From UniProt

complete

part_of

GO:0098978

glutamatergic synapse

PMID:16000618[1]

ECO:0006054

pharmacological assay evidence used in manual assertion

C

part_of:(UBERON:0002421)

Seeded From UniProt

complete

part_of

GO:0098978

glutamatergic synapse

PMID:16000618[1]

ECO:0006042

cell fractionation evidence used in manual assertion

C

part_of:(UBERON:0002421)

Seeded From UniProt

complete

part_of

GO:0098978

glutamatergic synapse

PMID:16000618[1]

ECO:0000279

western blot evidence used in manual assertion

C

part_of:(UBERON:0002421)

Seeded From UniProt

complete

part_of

GO:0016324

apical plasma membrane

PMID:11557527[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0016323

basolateral plasma membrane

PMID:11557527[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

PMID:11557527[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0035589

G protein-coupled purinergic nucleotide receptor signaling pathway

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0045028

P

Seeded From UniProt

complete

involved_in

GO:0071380

cellular response to prostaglandin E stimulus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9JJS7
ensembl:ENSMUSP00000055869

P

Seeded From UniProt

complete

enables

GO:0045030

UTP-activated nucleotide receptor activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9JJS7
ensembl:ENSMUSP00000055869

F

Seeded From UniProt

complete

involved_in

GO:0030321

transepithelial chloride transport

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9JJS7
ensembl:ENSMUSP00000055869

P

Seeded From UniProt

complete

enables

GO:0004930

G protein-coupled receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000276

F

Seeded From UniProt

complete

involved_in

GO:0007186

G protein-coupled receptor signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000018
InterPro:IPR000276

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000018
InterPro:IPR000276
InterPro:IPR017452

C

Seeded From UniProt

complete

involved_in

GO:0030321

transepithelial chloride transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000018

P

Seeded From UniProt

complete

enables

GO:0045028

G protein-coupled purinergic nucleotide receptor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000018

F

Seeded From UniProt

complete

involved_in

GO:0007186

G protein-coupled receptor signaling pathway

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0297

P

Seeded From UniProt

complete

enables

GO:0004930

G protein-coupled receptor activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0297

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

involved_in

GO:0007165

signal transduction

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0807

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 Rodrigues, RJ et al. (2005) Dual presynaptic control by ATP of glutamate release via facilitatory P2X1, P2X2/3, and P2X3 and inhibitory P2Y1, P2Y2, and/or P2Y4 receptors in the rat hippocampus. J. Neurosci. 25 6286-95 PubMed GONUTS page
  2. 2.0 2.1 2.2 Dranoff, JA et al. (2001) Polarized expression and function of P2Y ATP receptors in rat bile duct epithelia. Am. J. Physiol. Gastrointest. Liver Physiol. 281 G1059-67 PubMed GONUTS page