GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
RAT:CAH3
Contents
| Species (Taxon ID) | Rattus norvegicus (Rat). (10116) | |
| Gene Name(s) | Ca3 | |
| Protein Name(s) | Carbonic anhydrase 3
Carbonate dehydratase III Carbonic anhydrase III CA-III | |
| External Links | ||
| UniProt | P14141 | |
| EMBL | M22413 AB030829 AB030830 AF037072 BC061980 | |
| PIR | I52551 | |
| RefSeq | NP_062165.2 XP_006232178.1 | |
| UniGene | Rn.1647 | |
| PDB | 1FLJ | |
| PDBsum | 1FLJ | |
| ProteinModelPortal | P14141 | |
| SMR | P14141 | |
| MINT | MINT-4569746 | |
| STRING | 10116.ENSRNOP00000014177 | |
| PhosphoSite | P14141 | |
| PaxDb | P14141 | |
| PRIDE | P14141 | |
| Ensembl | ENSRNOT00000014180 | |
| GeneID | 54232 | |
| KEGG | rno:54232 | |
| UCSC | RGD:2241 | |
| CTD | 12350 | |
| RGD | 2241 | |
| eggNOG | COG3338 | |
| GeneTree | ENSGT00760000118915 | |
| HOGENOM | HOG000112637 | |
| HOVERGEN | HBG002837 | |
| InParanoid | P14141 | |
| KO | K01672 | |
| OMA | EAPFTHF | |
| OrthoDB | EOG7WMCK7 | |
| PhylomeDB | P14141 | |
| TreeFam | TF316425 | |
| BRENDA | 4.2.1.1 | |
| Reactome | REACT_199186 | |
| EvolutionaryTrace | P14141 | |
| NextBio | 610666 | |
| PRO | PR:P14141 | |
| Proteomes | UP000002494 | |
| Genevestigator | P14141 | |
| GO | GO:0005829 GO:0004089 GO:0016151 GO:0008270 GO:0006730 GO:0045471 GO:0006979 | |
| Gene3D | 3.10.200.10 | |
| InterPro | IPR001148 IPR023561 IPR018338 IPR018441 | |
| PANTHER | PTHR18952 PTHR18952:SF96 | |
| Pfam | PF00194 | |
| SMART | SM01057 | |
| SUPFAM | SSF51069 | |
| PROSITE | PS00162 PS51144 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0016791 |
phosphatase activity |
ECO:0000314 |
F |
Figure 3 |
complete | |||||
|
enables |
GO:0016791 |
phosphatase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045471 |
response to ethanol |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006979 |
response to oxidative stress |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016311 |
dephosphorylation |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0016791 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016151 |
nickel cation binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P16015 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0009617 |
response to bacterium |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P16015 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P16015 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004089 |
carbonate dehydratase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008270 |
zinc ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004089 |
carbonate dehydratase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004089 |
carbonate dehydratase activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016829 |
lyase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Cabiscol, E & Levine, RL (1996) The phosphatase activity of carbonic anhydrase III is reversibly regulated by glutathiolation. Proc. Natl. Acad. Sci. U.S.A. 93 4170-4 PubMed GONUTS page
- ↑ 2.0 2.1 Kharbanda, KK et al. (2009) Proteomics reveal a concerted upregulation of methionine metabolic pathway enzymes, and downregulation of carbonic anhydrase-III, in betaine supplemented ethanol-fed rats. Biochem. Biophys. Res. Commun. 381 523-7 PubMed GONUTS page
- ↑ 3.0 3.1 Ikeda, M et al. (2000) Suppression of carbonic anhydrase III in rat liver by a dioxin-related toxic compound, coplanar polychlorinated biphenyl, 3, 3',4,4',5-pentachlorobiphenyl. Arch. Biochem. Biophys. 380 159-64 PubMed GONUTS page
