RAT:BASI

Species (Taxon ID)	Rattus norvegicus (Rat). (10116)
Gene Name(s)	Bsg
Protein Name(s)	Basigin Glycoprotein CE9 OX-47 antigen
External Links
UniProt	P26453
EMBL	X54640 X67215 AY120888
PIR	S15674
RefSeq	NP_001103352.1 NP_036915.1
UniGene	Rn.2269
ProteinModelPortal	P26453
IntAct	P26453
MINT	MINT-4996604
PhosphoSite	P26453
PaxDb	P26453
PRIDE	P26453
Ensembl	ENSRNOT00000011275 ENSRNOT00000044275
GeneID	25246
KEGG	rno:25246
UCSC	RGD:2220
CTD	682
RGD	2220
eggNOG	NOG83713
GeneTree	ENSGT00390000010516
HOGENOM	HOG000263411
HOVERGEN	HBG008120
InParanoid	P26453
KO	K06535
OMA	ELHCEAV
OrthoDB	EOG7V1FQN
PhylomeDB	P26453
Reactome	REACT_199178 REACT_203088 REACT_245266 REACT_252097
NextBio	605849
PRO	PR:P26453
Proteomes	UP000002494
ExpressionAtlas	P26453
Genevestigator	P26453
GO	GO:0002080 GO:0070062 GO:0005887 GO:0042470 GO:0045121 GO:0005739 GO:0042383 GO:0005537 GO:0046697 GO:0007566 GO:0042475 GO:0072661 GO:0051591 GO:0046689 GO:0043434
Gene3D	2.60.40.10
InterPro	IPR009151 IPR007110 IPR013783 IPR013098 IPR003599 IPR003598
PANTHER	PTHR10075:SF12
Pfam	PF07679
SMART	SM00409 SM00408
PROSITE	PS50835

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0072659	protein localization to plasma membrane	PMID:10921872^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005887	integral component of plasma membrane	PMID:11719518^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0051591	response to cAMP	PMID:14607782^[3]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0046697	decidualization	PMID:12141934^[4]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0046689	response to mercury ion	PMID:15917240^[5]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0045121	membrane raft	PMID:17684756^[6]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0043434	response to peptide hormone	PMID:14607782^[3]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0042475	odontogenesis of dentin-containing tooth	PMID:17684756^[6]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0042383	sarcolemma	PMID:16434551^[7]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
involved_in	GO:0007566	embryo implantation	PMID:12141934^[4]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	PMID:16434551^[7]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
enables	GO:0098632	cell-cell adhesion mediator activity	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0010473 FB:FBgn0028482 PANTHER:PTN001296633	F	Seeded From UniProt	complete
involved_in	GO:0070593	dendrite self-avoidance	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0010473 MGI:MGI:1196281 MGI:MGI:2150309 PANTHER:PTN001296633 UniProtKB:A0A0B4K823	P	Seeded From UniProt	complete
part_of	GO:0030424	axon	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:104750 MGI:MGI:1196281 PANTHER:PTN001296633 RGD:2322545 UniProtKB:A0A0B4K823 UniProtKB:Q03696 WB:WBGene00004370 WB:WBGene00016354	C	Seeded From UniProt	complete
involved_in	GO:0007411	axon guidance	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0010473 MGI:MGI:104750 PANTHER:PTN001296633 UniProtKB:A0A0B4K823	P	Seeded From UniProt	complete
involved_in	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000635 FB:FBgn0028482 FB:FBgn0265296 PANTHER:PTN001296633 RGD:620296 UniProtKB:Q8TD84	P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:21873635^[8]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000635 MGI:MGI:104750 MGI:MGI:1196281 MGI:MGI:1858223 MGI:MGI:2444710 PANTHER:PTN001296633 UniProtKB:P35613 UniProtKB:Q8WX93	C	Seeded From UniProt	complete
part_of	GO:0002080	acrosomal membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P18572 ensembl:ENSMUSP00000070751	C	Seeded From UniProt	complete
part_of	GO:0043231	intracellular membrane-bounded organelle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P35613 ensembl:ENSP00000333769	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P35613 ensembl:ENSP00000333769	C	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR009151	C	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C	Seeded From UniProt	complete
enables	GO:0005537	mannose binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0465	F	Seeded From UniProt	complete
enables	GO:0030246	carbohydrate binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0430	F	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C	Seeded From UniProt	complete
part_of	GO:0042470	melanosome	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0161	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Kirk, P et al. (2000) CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression. EMBO J. 19 3896-904 PubMed GONUTS page
↑ Wilson, MC et al. (2002) Fluorescence resonance energy transfer studies on the interaction between the lactate transporter MCT1 and CD147 provide information on the topology and stoichiometry of the complex in situ. J. Biol. Chem. 277 3666-72 PubMed GONUTS page
↑ ^3.0 ^3.1 Fanelli, A et al. (2003) MCT1 and its accessory protein CD147 are differentially regulated by TSH in rat thyroid cells. Am. J. Physiol. Endocrinol. Metab. 285 E1223-9 PubMed GONUTS page
↑ ^4.0 ^4.1 Xiao, LJ et al. (2002) Basigin expression and hormonal regulation in the rat uterus during the peri-implantation period. Reproduction 124 219-25 PubMed GONUTS page
↑ Wilson, MC et al. (2005) Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is EMBIGIN (gp70). J. Biol. Chem. 280 27213-21 PubMed GONUTS page
↑ ^6.0 ^6.1 Schwab, W et al. (2007) Immunocytochemical and biochemical detection of EMMPRIN in the rat tooth germ: differentiation-dependent co-expression with MMPs and co-localization with caveolin-1 in membrane rafts of dental epithelial cells. Histochem. Cell Biol. 128 195-203 PubMed GONUTS page
↑ ^7.0 ^7.1 Hashimoto, T et al. (2006) Colocalization of MCT1, CD147, and LDH in mitochondrial inner membrane of L6 muscle cells: evidence of a mitochondrial lactate oxidation complex. Am. J. Physiol. Endocrinol. Metab. 290 E1237-44 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 ^8.3 ^8.4 ^8.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:10921872-1] Kirk, P et al. (2000) CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression. EMBO J. 19 3896-904 PubMed GONUTS page

[PMID:11719518-2] Wilson, MC et al. (2002) Fluorescence resonance energy transfer studies on the interaction between the lactate transporter MCT1 and CD147 provide information on the topology and stoichiometry of the complex in situ. J. Biol. Chem. 277 3666-72 PubMed GONUTS page

[PMID:14607782-3] 3.0 ^3.1 Fanelli, A et al. (2003) MCT1 and its accessory protein CD147 are differentially regulated by TSH in rat thyroid cells. Am. J. Physiol. Endocrinol. Metab. 285 E1223-9 PubMed GONUTS page

[PMID:12141934-4] 4.0 ^4.1 Xiao, LJ et al. (2002) Basigin expression and hormonal regulation in the rat uterus during the peri-implantation period. Reproduction 124 219-25 PubMed GONUTS page

[PMID:15917240-5] Wilson, MC et al. (2005) Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is EMBIGIN (gp70). J. Biol. Chem. 280 27213-21 PubMed GONUTS page

[PMID:17684756-6] 6.0 ^6.1 Schwab, W et al. (2007) Immunocytochemical and biochemical detection of EMMPRIN in the rat tooth germ: differentiation-dependent co-expression with MMPs and co-localization with caveolin-1 in membrane rafts of dental epithelial cells. Histochem. Cell Biol. 128 195-203 PubMed GONUTS page

[PMID:16434551-7] 7.0 ^7.1 Hashimoto, T et al. (2006) Colocalization of MCT1, CD147, and LDH in mitochondrial inner membrane of L6 muscle cells: evidence of a mitochondrial lactate oxidation complex. Am. J. Physiol. Endocrinol. Metab. 290 E1237-44 PubMed GONUTS page

[PMID:21873635-8] 8.0 ^8.1 ^8.2 ^8.3 ^8.4 ^8.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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RAT:BASI

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