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RAT:ATPB
Contents
| Species (Taxon ID) | Rattus norvegicus (Rat). (10116) | |
| Gene Name(s) | Atp5b | |
| Protein Name(s) | ATP synthase subunit beta, mitochondrial | |
| External Links | ||
| UniProt | P10719 | |
| EMBL | BC099743 M25301 M19044 M57634 | |
| PIR | A28701 A30160 | |
| RefSeq | NP_599191.1 | |
| UniGene | Rn.92965 | |
| PDB | 1MAB 2F43 | |
| PDBsum | 1MAB 2F43 | |
| ProteinModelPortal | P10719 | |
| SMR | P10719 | |
| BioGrid | 251212 | |
| IntAct | P10719 | |
| MINT | MINT-4587159 | |
| ChEMBL | CHEMBL2176796 | |
| PhosphoSite | P10719 | |
| UCD-2DPAGE | P10719 | |
| World-2DPAGE | 0004:P10719 | |
| PaxDb | P10719 | |
| PRIDE | P10719 | |
| GeneID | 171374 | |
| KEGG | rno:171374 | |
| UCSC | RGD:621368 | |
| CTD | 506 | |
| RGD | 621368 | |
| eggNOG | COG0055 | |
| HOGENOM | HOG000009605 | |
| HOVERGEN | HBG004307 | |
| InParanoid | P10719 | |
| KO | K02133 | |
| PhylomeDB | P10719 | |
| EvolutionaryTrace | P10719 | |
| NextBio | 622183 | |
| PRO | PR:P10719 | |
| Proteomes | UP000002494 | |
| Genevestigator | P10719 | |
| GO | GO:0005743 GO:0005753 GO:0000275 GO:0005739 GO:0045261 GO:0005524 GO:0016887 GO:0005509 GO:0030228 GO:0046933 GO:0006172 GO:0006200 GO:0015991 GO:0046034 GO:0015986 GO:0006898 | |
| Gene3D | 1.10.1140.10 3.40.50.300 | |
| HAMAP | MF_01347 | |
| InterPro | IPR003593 IPR020003 IPR005722 IPR000793 IPR000194 IPR004100 IPR024034 IPR027417 | |
| Pfam | PF00006 PF00306 PF02874 | |
| SMART | SM00382 | |
| SUPFAM | SSF47917 SSF50615 SSF52540 | |
| TIGRFAMs | TIGR01039 | |
| PROSITE | PS00152 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0045121 |
membrane raft |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(CL:0002608) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005753 |
mitochondrial proton-transporting ATP synthase complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1905242 |
response to 3,3',5-triiodo-L-thyronine |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1904643 |
response to curcumin |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1901653 |
cellular response to peptide |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046034 |
ATP metabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0045261 |
proton-transporting ATP synthase complex, catalytic core F(1) |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0045261 |
proton-transporting ATP synthase complex, catalytic core F(1) |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0043531 |
ADP binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0030228 |
lipoprotein particle receptor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016887 |
ATPase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
contributes_to |
GO:0016887 |
ATPase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0010042 |
response to manganese ion |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0009986 |
cell surface |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009631 |
cold acclimation |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006898 |
receptor-mediated endocytosis |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005743 |
mitochondrial inner membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005743 |
mitochondrial inner membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005743 |
mitochondrial inner membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005509 |
calcium ion binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0001889 |
liver development |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000275 |
mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0099132 |
ATP hydrolysis coupled cation transmembrane transport |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0046933 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015986 |
ATP synthesis coupled proton transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0045261 |
proton-transporting ATP synthase complex, catalytic core F(1) |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0046034 |
ATP metabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046933 |
proton-transporting ATP synthase activity, rotational mechanism |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1902600 |
proton transmembrane transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0045261 |
proton-transporting ATP synthase complex, catalytic core F(1) |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006754 |
ATP biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005743 |
mitochondrial inner membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006811 |
ion transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Ledesma, MD et al. (2003) Proteomic characterisation of neuronal sphingolipid-cholesterol microdomains: role in plasminogen activation. Brain Res. 987 107-16 PubMed GONUTS page
- ↑ Meyer, B et al. (2007) Identification of two proteins associated with mammalian ATP synthase. Mol. Cell Proteomics 6 1690-9 PubMed GONUTS page
- ↑ Severino, V et al. (2011) Proteomic characterization of early changes induced by triiodothyronine in rat liver. J. Proteome Res. 10 3212-24 PubMed GONUTS page
- ↑ Qiu, P et al. (2016) Overdose Intake of Curcumin Initiates the Unbalanced State of Bodies. J. Agric. Food Chem. 64 2765-71 PubMed GONUTS page
- ↑ Yu, JH et al. (2003) Proteome analysis of rat pancreatic acinar cells: implication for cerulein-induced acute pancreatitis. Proteomics 3 2446-53 PubMed GONUTS page
- ↑ 6.0 6.1 Ko, YH et al. (2000) Mitochondrial F(0)F(1) ATP synthase. Subunit regions on the F1 motor shielded by F(0), Functional significance, and evidence for an involvement of the unique F(0) subunit F(6). J. Biol. Chem. 275 32931-9 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Pedersen, PL et al. (1987) Mitochondrial ATP synthase: dramatic Mg2+-induced alterations in the structure and function of the F1-ATPase moiety. Biochemistry 26 8631-7 PubMed GONUTS page
- ↑ 8.0 8.1 Bianchet, M et al. (1991) Mitochondrial ATP synthase. Quaternary structure of the F1 moiety at 3.6 A determined by x-ray diffraction analysis. J. Biol. Chem. 266 21197-201 PubMed GONUTS page
- ↑ 9.0 9.1 Garboczi, DN et al. (1988) Mitochondrial ATP synthase. Overexpression in Escherichia coli of a rat liver beta subunit peptide and its interaction with adenine nucleotides. J. Biol. Chem. 263 15694-8 PubMed GONUTS page
- ↑ 10.0 10.1 10.2 10.3 10.4 Martinez, LO et al. (2003) Ectopic beta-chain of ATP synthase is an apolipoprotein A-I receptor in hepatic HDL endocytosis. Nature 421 75-9 PubMed GONUTS page
- ↑ Zhang, S et al. (2005) Changes in the brain mitochondrial proteome of male Sprague-Dawley rats treated with manganese chloride. Toxicol. Appl. Pharmacol. 202 13-7 PubMed GONUTS page
- ↑ Osanai, T et al. (2009) Coupling factor 6 enhances Src-mediated responsiveness to angiotensin II in resistance arterioles and cells. Cardiovasc. Res. 81 780-7 PubMed GONUTS page
- ↑ Andersson, U et al. (1997) ATP synthase subunit c expression: physiological regulation of the P1 and P2 genes. Biochem. J. 323 ( Pt 2) 379-85 PubMed GONUTS page
- ↑ 14.0 14.1 Hubbard, MJ & McHugh, NJ (1996) Mitochondrial ATP synthase F1-beta-subunit is a calcium-binding protein. FEBS Lett. 391 323-9 PubMed GONUTS page
- ↑ Garboczi, DN et al. (1990) Rat liver mitochondrial ATP synthase. Effects of mutations in the glycine-rich region of a beta subunit peptide on its interaction with adenine nucleotides. J. Biol. Chem. 265 14632-7 PubMed GONUTS page
- ↑ Luis, AM et al. (1993) Translational regulation of mitochondrial differentiation in neonatal rat liver. Specific increase in the translational efficiency of the nuclear-encoded mitochondrial beta-F1-ATPase mRNA. J. Biol. Chem. 268 1868-75 PubMed GONUTS page
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