GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
RAT:AHI1
Contents
Species (Taxon ID) | Rattus norvegicus (Rat). (10116) | |
Gene Name(s) | Ahi1 | |
Protein Name(s) | Jouberin
Abelson helper integration site 1 protein homolog AHI-1 | |
External Links | ||
UniProt | Q6DTM3 | |
EMBL | AY647140 | |
RefSeq | NP_001002277.1 | |
UniGene | Rn.155144 | |
ProteinModelPortal | Q6DTM3 | |
STRING | 10116.ENSRNOP00000019077 | |
PaxDb | Q6DTM3 | |
PRIDE | Q6DTM3 | |
GeneID | 308923 | |
KEGG | rno:308923 | |
CTD | 54806 | |
RGD | 1303040 | |
eggNOG | COG2319 | |
HOGENOM | HOG000033864 | |
HOVERGEN | HBG080824 | |
InParanoid | Q6DTM3 | |
KO | K16740 | |
PhylomeDB | Q6DTM3 | |
NextBio | 659816 | |
PRO | PR:Q6DTM3 | |
Proteomes | UP000002494 | |
Genevestigator | Q6DTM3 | |
GO | GO:0005912 GO:0005911 GO:0005814 GO:0005813 GO:0036064 GO:0005929 GO:0031513 GO:0072372 GO:0036038 GO:0034613 GO:0007417 GO:0042384 GO:0060271 GO:0035844 GO:0001947 GO:0030902 GO:0070121 GO:0070986 GO:0001738 GO:0043066 GO:0071599 GO:0035845 GO:0030862 GO:0002092 GO:0045944 GO:0039023 GO:0039008 GO:0050795 GO:0010842 GO:0065001 GO:0007169 GO:0016192 | |
Gene3D | 2.130.10.10 | |
InterPro | IPR001452 IPR015943 IPR001680 IPR017986 | |
Pfam | PF00018 PF00400 | |
PRINTS | PR00452 | |
SMART | SM00326 SM00320 | |
SUPFAM | SSF50044 SSF50978 | |
PROSITE | PS50002 PS50082 PS50294 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0001934 |
positive regulation of protein phosphorylation |
ECO:0000314 |
P |
Suppressing Hap1 expression by siRNA also reduced the level of phosphorylated Erk and Akt (Figure 7C). Quantification of the ratio of phosphorylated Erk or Akt to the total amount of Erk and Akt confirmed the decreased phosphorylation of these proteins (Figure 7D). |
complete | |||||
part_of |
GO:0005929 |
cilium |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0071599 |
otic vesicle development |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0070986 |
left/right axis specification |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0070121 |
Kupffer's vesicle development |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0065001 |
specification of axis polarity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0060271 |
cilium assembly |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0050795 |
regulation of behavior |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0043066 |
negative regulation of apoptotic process |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0039023 |
pronephric duct morphogenesis |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0039008 |
pronephric nephron tubule morphogenesis |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0036064 |
ciliary basal body |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0036038 |
MKS complex |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0035845 |
photoreceptor cell outer segment organization |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0035844 |
cloaca development |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0034613 |
cellular protein localization |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0097730 |
non-motile cilium |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030902 |
hindbrain development |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030862 |
positive regulation of polarized epithelial cell differentiation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016192 |
vesicle-mediated transport |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0010842 |
retina layer formation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007417 |
central nervous system development |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007169 |
transmembrane receptor protein tyrosine kinase signaling pathway |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005929 |
cilium |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005912 |
adherens junction |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005911 |
cell-cell junction |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005814 |
centriole |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005813 |
centrosome |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0002092 |
positive regulation of receptor internalization |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0001947 |
heart looping |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0001738 |
morphogenesis of a polarized epithelium |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:1990403 |
embryonic brain development |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0046325 |
negative regulation of glucose import |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0032094 |
response to food |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0021510 |
spinal cord development |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005856 |
cytoskeleton |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007275 |
multicellular organism development |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030154 |
cell differentiation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005929 |
cilium |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030030 |
cell projection organization |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0042995 |
cell projection |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0030054 |
cell junction |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005814 |
centriole |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005912 |
adherens junction |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Sheng, G et al. (2008) Huntingtin-associated protein 1 interacts with Ahi1 to regulate cerebellar and brainstem development in mice. J. Clin. Invest. 118 2785-95 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Han, SB et al. (2009) Regulation of AHI1 expression in adult rat brain: Implication in hypothalamic feeding control. Biochem. Biophys. Res. Commun. 390 535-40 PubMed GONUTS page
- ↑ Prior, MJ et al. (2010) The characterization of Abelson helper integration site-1 in skeletal muscle and its links to the metabolic syndrome. Metab. Clin. Exp. 59 1057-64 PubMed GONUTS page
- ↑ Weng, L et al. (2013) Loss of Ahi1 affects early development by impairing BM88/Cend1-mediated neuronal differentiation. J. Neurosci. 33 8172-84 PubMed GONUTS page
c
- GO:0005911 ! cell-cell junction
- GO:0034613 ! cellular protein localization
- GO:0030154 ! cell differentiation
- GO:0030054 ! cell junction
- GO:0030030 ! cell projection organization
- GO:0042995 ! cell projection
- GO:0007169 ! cell surface receptor protein tyrosine kinase signaling pathway
- GO:0007417 ! central nervous system development
- GO:0005814 ! centriole
- GO:0005813 ! centrosome
- Chordata
- GO:0036064 ! ciliary basal body
- GO:0005929 ! cilium
- GO:0060271 ! cilium assembly
- GO:0035844 ! cloaca development
- Craniata
- GO:0005737 ! cytoplasm
- GO:0005856 ! cytoskeleton
g
m
n
p
- GO:0035845 ! photoreceptor cell outer segment organization
- GO:0001934 ! positive regulation of protein phosphorylation
- GO:0030862 ! positive regulation of polarized epithelial cell differentiation
- GO:0002092 ! positive regulation of receptor internalization
- GO:0045944 ! positive regulation of transcription by RNA polymerase II
- GO:0039023 ! pronephric duct morphogenesis
- GO:0039008 ! pronephric nephron tubule morphogenesis
r