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RAT:6PGD
Contents
| Species (Taxon ID) | Rattus norvegicus (Rat). (10116) | |
| Gene Name(s) | Pgd (ECO:0000250 with UniProtKB:P00349) | |
| Protein Name(s) | 6-phosphogluconate dehydrogenase, decarboxylating (ECO:0000250 with UniProtKB:P00349) | |
| External Links | ||
| UniProt | P85968 | |
| EMBL | AABR03040409 | |
| RefSeq | XP_002729611.1 XP_003754166.1 | |
| ProteinModelPortal | P85968 | |
| PhosphoSite | P85968 | |
| World-2DPAGE | 0004:P85968 | |
| PaxDb | P85968 | |
| PRIDE | P85968 | |
| GeneID | 100360180 | |
| KEGG | rno:100360180 | |
| RGD | 1583832 | |
| eggNOG | COG5059 | |
| HOGENOM | HOG000255147 | |
| HOVERGEN | HBG000029 | |
| InParanoid | P85968 | |
| KO | K00033 | |
| SABIO-RK | P85968 | |
| UniPathway | UPA00115 | |
| PRO | PR:P85968 | |
| Proteomes | UP000002494 | |
| Genevestigator | P85968 | |
| GO | GO:0005737 GO:0043231 GO:0030246 GO:0031406 GO:0050661 GO:0004616 GO:0005975 GO:0019521 GO:0006739 GO:0006098 GO:0009051 | |
| Gene3D | 1.10.1040.10 1.20.5.320 3.40.50.720 | |
| InterPro | IPR008927 IPR006114 IPR006113 IPR006115 IPR006184 IPR013328 IPR012284 IPR016040 | |
| Pfam | PF00393 PF03446 | |
| PIRSF | PIRSF000109 | |
| SUPFAM | SSF48179 | |
| TIGRFAMs | TIGR00873 | |
| PROSITE | PS00461 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0004616 |
phosphogluconate dehydrogenase (decarboxylating) activity |
ECO:0000314 |
F |
See Figure 1 for 6PGD activity. |
complete | |||||
|
enables |
GO:0004616 |
phosphogluconate dehydrogenase (decarboxylating) activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006098 |
pentose-phosphate shunt |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004616 |
phosphogluconate dehydrogenase (decarboxylating) activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050661 |
NADP binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050661 |
NADP binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0043231 |
intracellular membrane-bounded organelle |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0043231 |
intracellular membrane-bounded organelle |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0031406 |
carboxylic acid binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0031406 |
carboxylic acid binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0030246 |
carbohydrate binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019521 |
D-gluconate metabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009051 |
pentose-phosphate shunt, oxidative branch |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006739 |
NADP metabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006098 |
pentose-phosphate shunt |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0005975 |
carbohydrate metabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004616 |
phosphogluconate dehydrogenase (decarboxylating) activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004616 |
phosphogluconate dehydrogenase (decarboxylating) activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004616 |
phosphogluconate dehydrogenase (decarboxylating) activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004616 |
phosphogluconate dehydrogenase (decarboxylating) activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR006113 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006098 |
pentose-phosphate shunt |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050661 |
NADP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR006113 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004616 |
phosphogluconate dehydrogenase (decarboxylating) activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019521 |
D-gluconate metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006098 |
pentose-phosphate shunt |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0570 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Adem, S & Ciftci, M (2012) Purification of rat kidney glucose 6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, and glutathione reductase enzymes using 2',5'-ADP Sepharose 4B affinity in a single chromatography step. Protein Expr. Purif. 81 1-4 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Hino, Y & Minakami, S (1982) Hexose-6-phosphate and 6-phosphogluconate dehydrogenases of rat liver microsomes. Involvement in NADPH and carbon dioxide generation in the luminal space of microsomal vesicles. J. Biochem. 92 547-57 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Tylicki, A et al. (2007) Effect of anabolic steroid nandrolone decanoate on the properties of certain enzymes in the heart, liver, and muscle of rats, and their effect on rats' cardiac electrophysiology. Horm. Metab. Res. 39 268-72 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Bublitz, C & Steavenson, S (1988) The pentose phosphate pathway in the endoplasmic reticulum. J. Biol. Chem. 263 12849-53 PubMed GONUTS page
- ↑ Zimmer, HG (1998) Significance of the 5-phosphoribosyl-1-pyrophosphate pool for cardiac purine and pyrimidine nucleotide synthesis: studies with ribose, adenine, inosine, and orotic acid in rats. Cardiovasc Drugs Ther 12 Suppl 2 179-87 PubMed GONUTS page
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