GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

RAT:5NTD

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Rattus norvegicus (Rat). (10116)
Gene Name(s) Nt5e (synonyms: Nt5, Nte)
Protein Name(s) 5'-nucleotidase

5'-NT Ecto-5'-nucleotidase

External Links
UniProt P21588
EMBL J05214
PIR A35036
UniGene Rn.40132
ProteinModelPortal P21588
BindingDB P21588
ChEMBL CHEMBL1075214
PhosphoSite P21588
PaxDb P21588
PRIDE P21588
UCSC RGD:61956
RGD 61956
eggNOG COG0737
HOGENOM HOG000247215
HOVERGEN HBG000026
InParanoid P21588
PhylomeDB P21588
PRO PR:P21588
Proteomes UP000002494
Genevestigator P21588
GO GO:0031225
GO:0009986
GO:0016021
GO:0097060
GO:0008253
GO:0008198
GO:0000166
GO:0046085
GO:0006196
GO:0007420
GO:0016311
GO:0046889
GO:0006164
GO:0010044
Gene3D 3.60.21.10
3.90.780.10
InterPro IPR008334
IPR006146
IPR006179
IPR004843
IPR029052
PANTHER PTHR11575
Pfam PF02872
PF00149
PRINTS PR01607
SUPFAM SSF55816
SSF56300
PROSITE PS00785
PS00786

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0005886

endomembrane system

PMID:6017738[1]

ECO:0000314

C

Table 2 and Fig 1

complete
CACAO 6666

GO:0008253

5'-nucleotidase activity

PMID:6017738[1]

ECO:0000314

F

Fig 1

complete
CACAO 6709

enables

GO:0008253

5'-nucleotidase activity

PMID:6017738[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:6017738[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0097060

synaptic membrane

PMID:21414400[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0046889

positive regulation of lipid biosynthetic process

PMID:21372807[3]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0046085

adenosine metabolic process

PMID:12675911[4]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0010044

response to aluminum ion

PMID:17686601[5]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

PMID:21627568[6]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0008253

5'-nucleotidase activity

PMID:12675911[4]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0008253

5'-nucleotidase activity

PMID:11935367[7]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0008198

ferrous iron binding

PMID:11935367[7]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0007420

brain development

PMID:21414400[2]

ECO:0000270

expression pattern evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006196

AMP catabolic process

PMID:21414400[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0016311

dephosphorylation

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0008253

P

Seeded From UniProt

complete

involved_in

GO:0016311

dephosphorylation

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0008253

P

Seeded From UniProt

complete

involved_in

GO:0016311

dephosphorylation

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0008253

P

Seeded From UniProt

complete

involved_in

GO:0016311

dephosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0008253

P

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006146

F

Seeded From UniProt

complete

involved_in

GO:0009166

nucleotide catabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006179
InterPro:IPR008334
InterPro:IPR036907

P

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004843
InterPro:IPR006179
InterPro:IPR008334
InterPro:IPR036907

F

Seeded From UniProt

complete

enables

GO:0016788

hydrolase activity, acting on ester bonds

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006146

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR006146

F

Seeded From UniProt

complete

enables

GO:0008253

5'-nucleotidase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:3.1.3.5

F

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

PMID:11935367[7]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

part_of

GO:0031225

anchored component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0336

C

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Song, CS & Bodansky, O (1967) Subcellular localization and properties of 5'-nucleotidase in the rat liver. J. Biol. Chem. 242 694-9 PubMed GONUTS page
  2. 2.0 2.1 2.2 Stanojević, I et al. (2011) Ontogenetic profile of ecto-5'-nucleotidase in rat brain synaptic plasma membranes. Int. J. Dev. Neurosci. 29 397-403 PubMed GONUTS page
  3. Müller, G et al. (2011) Upregulation of lipid synthesis in small rat adipocytes by microvesicle-associated CD73 from large adipocytes. Obesity (Silver Spring) 19 1531-44 PubMed GONUTS page
  4. 4.0 4.1 Mackiewicz, M et al. (2003) Enzymes of adenosine metabolism in the brain: diurnal rhythm and the effect of sleep deprivation. J. Neurochem. 85 348-57 PubMed GONUTS page
  5. Kaizer, RR et al. (2007) The effect of aluminium on NTPDase and 5'-nucleotidase activities from rat synaptosomes and platelets. Int. J. Dev. Neurosci. 25 381-6 PubMed GONUTS page
  6. Tan, Q et al. (2012) Effect of in vitro passaging on the stem cell-related properties of tendon-derived stem cells-implications in tissue engineering. Stem Cells Dev. 21 790-800 PubMed GONUTS page
  7. 7.0 7.1 7.2 Kocic, G et al. (2001) Oxidative modification of rat liver 5'-nucleotidase: the mechanisms for protection and re-activation. Arch. Physiol. Biochem. 109 323-30 PubMed GONUTS page