PYRFU:CAS6

Species (Taxon ID)	Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1). (186497)
Gene Name(s)	cas6
Protein Name(s)	CRISPR-associated endoribonuclease Cas6
External Links
UniProt	Q8U1S4
EMBL	AE009950
RefSeq	NP_578860.1
PDB	3I4H 3PKM
PDBsum	3I4H 3PKM
STRING	186497.PF1131
PRIDE	Q8U1S4
EnsemblBacteria	AAL81255
GeneID	1469000
KEGG	pfu:PF1131
eggNOG	COG1583
HOGENOM	HOG000153717
OMA	GFFYFST
EvolutionaryTrace	Q8U1S4
Proteomes	UP000001013
GO	GO:0004519 GO:0003723
InterPro	IPR010156
Pfam	PF01881
PIRSF	PIRSF005054
TIGRFAMs	TIGR01877

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0043571	maintenance of CRISPR repeat elements	PMID:19141480	ECO:0000314			P		Figure 1 shows that cas6 cleaves RNA in repeat sequences of CRISPR elements.	complete CACAO 10046
involved_in	GO:0043571	maintenance of CRISPR repeat elements	PMID:19141480	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0090305	nucleic acid phosphodiester bond hydrolysis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004519	P		Seeded From UniProt	complete
involved_in	GO:0090305	nucleic acid phosphodiester bond hydrolysis	GO_REF:0000108	ECO:0000366	evidence based on logical inference from automatic annotation used in automatic assertion	GO:0004518	P		Seeded From UniProt	complete
enables	GO:0016788	hydrolase activity, acting on ester bonds	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR010156	F		Seeded From UniProt	complete
involved_in	GO:0051607	defense response to virus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0051	P		Seeded From UniProt	complete
enables	GO:0003723	RNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0694	F		Seeded From UniProt	complete
enables	GO:0004519	endonuclease activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0255	F		Seeded From UniProt	complete
enables	GO:0004518	nuclease activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0540	F		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
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References

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