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PSEAI:V6AMP2

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Species (Taxon ID) Pseudomonas aeruginosa MH27. (1306165)
Gene Name(s) fimX (ECO:0000313 with EMBL:CDH80023.1)
Protein Name(s) Protein FimX (ECO:0000313 with EMBL:CDH80023.1)
External Links
UniProt V6AMP2
EMBL CBTR010000027
RefSeq WP_003095680.1
ProteinModelPortal V6AMP2
SMR V6AMP2
EnsemblBacteria CDH80023
Proteomes UP000018200
GO GO:0000160
GO:0006355
CDD cd01948
cd01949
cd00130
Gene3D 3.20.20.450
InterPro IPR011006
IPR001633
IPR035919
IPR000160
IPR029787
IPR000014
IPR035965
IPR013767
IPR001789
Pfam PF00563
PF00990
PF00989
SMART SM00052
SM00267
SUPFAM SSF141868
SSF52172
SSF55073
SSF55785
TIGRFAMs TIGR00254
TIGR00229
PROSITE PS50883
PS50887
PS50110

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0000160

phosphorelay signal transduction system

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001789

P

Seeded From UniProt

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013767

P

Seeded From UniProt

involved_in

GO:0000160

phosphorelay signal transduction system

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001789

P

Seeded From UniProt

GO:0043107

type IV pilus-dependent motility

PMID:16677312[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

FimX is required for twitching motility, as seen in Table 1.

Organism: Pseudomonas aeruginosa

complete
CACAO 13004

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013767

P

Seeded From UniProt

GO:0071111

cyclic-guanylate-specific phosphodiesterase activity

PMID:16677312[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

FimX exhibits phosphodiesterase activity which is stimulated by GTP, as seen in Figure 5. Organism: Pseudomonas aeruginosa

complete
CACAO 13005

GO:0043683

type IV pilus biogenesis

PMID:16677312[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Determination of surface pili by enzyme-linked immunosorbent assay (ELISA) showed that bacteria expressing either point mutant allele of FimX failed to assemble surface pili (Fig. 4B). Thus the GGDEF and EAL domains appear to be critical for FimX function in vivo, and both the EVL and non-canonical GDSIF motifs are functionally essential. Organism: Pseudomonas aeruginosa

complete
CACAO 13014

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Kazmierczak, BI et al. (2006) Analysis of FimX, a phosphodiesterase that governs twitching motility in Pseudomonas aeruginosa. Mol. Microbiol. 60 1026-43 PubMed GONUTS page