PSEAI:Q9RLJ1

Species (Taxon ID)	Pseudomonas aeruginosa. (287)
Gene Name(s)	czrR (ECO:0000313 with EMBL:CAB56468.1)
Protein Name(s)	CzcR (ECO:0000313 with EMBL:ACX81358.1) CzrR protein (ECO:0000313 with EMBL:CAB56468.1) Transcriptional activator protein CzcR (ECO:0000313 with EMBL:ALI58822.1) Two-component system response regulator (ECO:0000313 with EMBL:KSC82161.1)
External Links
UniProt	Q9RLJ1
EMBL	GU017677 KC147685 KC147686 KC147687 KT454971 CP012901 Y14018 CDAZ01000029 CVVJ01000163 CVWF01000643 LLLN01000056 LLOD01000035
PIR	H83330
RefSeq	WP_003089900.1
STRING	208964.PA2523
EnsemblBacteria	CEI21476 CRP83944 CRR53776 KQB29988 KQC54974 KQC63136 KQC64934 KQC68247 KQC77398 KQJ53850 KQJ61597 KQJ67569 KQJ75631 KQJ79905 KQK54395 KQK55354 KRU76692 KRU88234 KRU91563 KRU94874 KRU95332 KRV01882 KRV07291 KRV15264 KRV21688 KRV29030 KRV34426 KSC82161 KSG18783 KSH12720
KEGG	paeb:NCGM1900_4004
PATRIC	19839515
PseudoCAP	PA2523
eggNOG	ENOG4105CK6 COG0745
HOGENOM	HOG000034815
KO	K07665
Proteomes	UP000042235 UP000043988 UP000054218 UP000054840
GO	GO:0005622 GO:0003677 GO:1900377 GO:0000160 GO:0043902 GO:0045862 GO:1900233 GO:0032411 GO:0006355
CDD	cd00383
Gene3D	1.10.10.10
InterPro	IPR011006 IPR001867 IPR006291 IPR016032 IPR001789 IPR011991
PANTHER	PTHR26402:SF684
Pfam	PF00072 PF00486
SMART	SM00448 SM00862
SUPFAM	SSF46894 SSF52172
TIGRFAMs	TIGR01387
PROSITE	PS51755 PS50110

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0009405	pathogenesis	PMID:22666466	ECO:0000316		UniProtKB:M4NAR4	P		Pseudomonas aeruginosa (PA01 Strain) czcR "Figure 4 CzcR is required for the full virulence of P. aeruginosa." " In our assay, an infection with the wild type strain killed 50% of the population within circa 3 days of contact with bacteria and all worms were dead after 4 days (Fig. 4). In contrast, the virulence of the ΔczcRS mutant was significantly reduced since 50% of the worms were still alive after 5 days of contact. The virulence of the ΔczcRS mutant strain complemented with czcR on the pRWT plasmid was partially restored since 50% of the worms were dead after 4 days and less than 20% of the worm population was alive after 5 days, while no complementation was observed with the czcS gene (Fig. 4).	complete CACAO 12487
involved_in	GO:1900377	negative regulation of secondary metabolite biosynthetic process	PMID:22666466	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:1900233	positive regulation of single-species biofilm formation on inanimate substrate	PMID:22666466	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045862	positive regulation of proteolysis	PMID:22666466	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043902	positive regulation of multi-organism process	PMID:22666466	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0032411	positive regulation of transporter activity	PMID:14679195	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0000160	phosphorelay signal transduction system	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001789 InterPro:IPR001867	P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001867 InterPro:IPR006291 InterPro:IPR016032	F		Seeded From UniProt	complete
involved_in	GO:0006355	regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001867 InterPro:IPR006291 InterPro:IPR016032	P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
involved_in	GO:0000160	phosphorelay signal transduction system	GO_REF:0000038	ECO:0000323	imported automatically asserted information used in automatic assertion	UniProtKB-KW:KW-0902	P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000414392	F		Seeded From UniProt	complete
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References

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