GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

PSEAI:P95429

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Pseudomonas aeruginosa. (287)
Gene Name(s) exsD (ECO:0000313 with EMBL:AAC44772.1)
Protein Name(s) ExsD (ECO:0000313 with EMBL:AAC44772.1)

Putative exsD (ECO:0000313 with EMBL:KFL13946.1)

External Links
UniProt P95429
EMBL U56077
HG974234
JMQH01000018
JOVK01000001
IntAct P95429

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0003677

DNA binding

PMID:19235906[1]

ECO:0000255

PMID:8578593[2]


F

Figure 2. Superposition and comparison with suspected binding protein and known DNA binding protein subdomains

complete
CACAO 9128

GO:0045892

negative regulation of transcription, DNA-templated

PMID:23279839[3]

ECO:0000314

P

Figure 1 A & B shows the diminished transcript levels in the presence of ExsD compared to ExsA, additionally it shows the decline of transcript levels in the presence of increased concentrations of ExsD.

complete
CACAO 10070

involved_in

GO:0045892

negative regulation of transcription, DNA-templated

PMID:23279839[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Bernhards, RC et al. (2009) Structural evidence suggests that antiactivator ExsD from Pseudomonas aeruginosa is a DNA binding protein. Protein Sci. 18 503-13 PubMed GONUTS page
  2. Holm, L & Sander, C (1995) Dali: a network tool for protein structure comparison. Trends Biochem. Sci. 20 478-80 PubMed GONUTS page
  3. 3.0 3.1 Bernhards, RC et al. (2013) Self-trimerization of ExsD limits inhibition of the Pseudomonas aeruginosa transcriptional activator ExsA in vitro. FEBS J. 280 1084-94 PubMed GONUTS page