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PSEAI:P77568

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Species (Taxon ID) Pseudomonas aeruginosa. (287)
Gene Name(s) algZ (ECO:0000313 with EMBL:AAB08056.1) (synonyms: fimS (ECO:0000313 with EMBL:AAA88426.2))
Protein Name(s) AlgZ (ECO:0000313 with EMBL:AAB08056.1)

Alginate O-acetyltransferase (ECO:0000313 with EMBL:KDR46391.1) Alginate biosynthesis protein (ECO:0000313 with EMBL:BAP25120.1) Alginate biosynthesis protein AlgZ/FimS (ECO:0000313 with EMBL:CDO84384.1) FimS (ECO:0000313 with EMBL:AAA88426.2) Histidine kinase family protein (ECO:0000313 with EMBL:KFL09542.1)

External Links
UniProt P77568
EMBL L48729
U52431
U50713
AP014622
AP014646
HG974234
JJOD01000077
JHEU01000076
JFJU01000004
JOVK01000001
JPQQ01000006
JMBS01000009
JMBR01000052
PIR D82989
RefSeq NP_253949.1
STRING 208964.PA5262
DNASU 879635
GeneID 879635
KEGG pae:PA5262
PATRIC 19845377
PseudoCAP PA5262
HOGENOM HOG000219788
KO K08082
OrthoDB EOG6P333M
GO GO:0016021
GO:0000155
GO:0000160
GO:2000147
GO:0043107
InterPro IPR010559
Pfam PF06580

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0043107

type IV pilus-dependent motility

PMID:8790418[1]

ECO:0000315

P

Fig. 3: MUTANT PHENOTYPE: Mutations in fimS result in either complete loss or severe retardation of twitching motility.

Fig 4: ELISA ASSAY: fimS mutant essentially lacks surface fimbriae as shown by ELISA, which is a sensitive quantitative assay.

complete
CACAO 4464

involved_in

GO:0043107

type IV pilus-dependent motility

PMID:8790418[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:2000147

positive regulation of cell motility

PMID:8790418[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0000160

phosphorelay signal transduction system

PMID:8790418[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0018106

peptidyl-histidine phosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004673

P

Seeded From UniProt

complete

involved_in

GO:0023014

signal transduction by protein phosphorylation

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0000155

P

Seeded From UniProt

complete

enables

GO:0000155

phosphorelay sensor kinase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010559

F

Seeded From UniProt

complete

involved_in

GO:0000160

phosphorelay signal transduction system

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010559

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR010559

C

Seeded From UniProt

complete

enables

GO:0004673

protein histidine kinase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.7.13.3

F

Seeded From UniProt

complete

involved_in

GO:0016310

phosphorylation

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0418

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

enables

GO:0016301

kinase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0418

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Whitchurch, CB et al. (1996) The alginate regulator AlgR and an associated sensor FimS are required for twitching motility in Pseudomonas aeruginosa. Proc. Natl. Acad. Sci. U.S.A. 93 9839-43 PubMed GONUTS page