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PSEAI:CPDA
Contents
| Species (Taxon ID) | Pseudomonas aeruginosa. (287) | |
| Gene Name(s) | cpdA (ECO:0000255 with HAMAP-Rule:MF_00905) | |
| Protein Name(s) | 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA (ECO:0000255 with HAMAP-Rule:MF_00905)
3',5'-cyclic AMP phosphodiesterase (ECO:0000255 with HAMAP-Rule:MF_00905) cAMP phosphodiesterase (ECO:0000255 with HAMAP-Rule:MF_00905) | |
| External Links | ||
| UniProt | D4P095 | |
| EMBL | GU551724 | |
| ProteinModelPortal | D4P095 | |
| GO | GO:0004115 GO:0046872 GO:0000166 | |
| Gene3D | 3.60.21.10 | |
| HAMAP | MF_00905 | |
| InterPro | IPR004843 IPR026575 IPR029052 | |
| Pfam | PF00149 | |
| SUPFAM | SSF56300 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0004115 |
3',5'-cyclic-AMP phosphodiesterase activity |
ECO:0000315 |
F |
Fig 2A shows that the mutant cpdA results in increased cellular cAMP, i.e. diminished 3',5'-cyclic-AMP phosphodiesterase activity. |
complete | |||||
| GO:0004115 |
3',5'-cyclic-AMP phosphodiesterase activity |
ECO:0000314 |
F |
Figure 1B shows phosphodiesterase activity assay |
complete | |||||
| GO:0004115 |
3',5'-cyclic-AMP phosphodiesterase activity |
ECO:0000247 |
F |
Figure 1A |
Missing: with/from | |||||
|
enables |
GO:0004115 |
3',5'-cyclic-AMP phosphodiesterase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000100331 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004115 |
3',5'-cyclic-AMP phosphodiesterase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000100331 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000100331 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Fuchs, EL et al. (2010) In vitro and in vivo characterization of the Pseudomonas aeruginosa cyclic AMP (cAMP) phosphodiesterase CpdA, required for cAMP homeostasis and virulence factor regulation. J. Bacteriol. 192 2779-90 PubMed GONUTS page
