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PSEAE:PBP5

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Species (Taxon ID) Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG12228). (208964)
Gene Name(s) pbpG
Protein Name(s) D-alanyl-D-alanine endopeptidase

DD-endopeptidase Penicillin-binding protein 5 PBP-5

External Links
UniProt P72161
EMBL U62582
AE004091
PIR B83538
RefSeq NP_249560.1
ProteinModelPortal P72161
SMR P72161
STRING 208964.PA0869
DrugBank DB00438
MEROPS S11.002
DNASU 877694
EnsemblBacteria AAG04258
GeneID 877694
KEGG pae:PA0869
PATRIC 19836022
PseudoCAP PA0869
eggNOG COG1686
HOGENOM HOG000199620
InParanoid P72161
KO K07262
OMA WDIKLTK
OrthoDB EOG6RJV2H
PhylomeDB P72161
Proteomes UP000002438
GO GO:0042597
GO:0009002
GO:0071555
GO:0009252
GO:0008360
Gene3D 3.40.710.10
InterPro IPR012338
IPR018044
IPR001967
Pfam PF00768
PRINTS PR00725
SUPFAM SSF56601

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0009002

serine-type D-Ala-D-Ala carboxypeptidase activity

PMID:23629710[1]

ECO:0000314

F

The DD carboxypeptidase activity was demonstrated through the use of a fluorescence based assay. Table 1 shows the kinetic parameters for the carboxypeptidase activity of Pa sPbP5 at pH 9.5.

complete
CACAO 8327

enables

GO:0009002

serine-type D-Ala-D-Ala carboxypeptidase activity

PMID:23629710[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004175

endopeptidase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG12015
PANTHER:PTN000491515

F

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001967
InterPro:IPR018044

P

Seeded From UniProt

complete

enables

GO:0009002

serine-type D-Ala-D-Ala carboxypeptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001967
InterPro:IPR018044

F

Seeded From UniProt

complete

involved_in

GO:0009252

peptidoglycan biosynthetic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0573

P

Seeded From UniProt

complete

involved_in

GO:0008360

regulation of cell shape

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0133

P

Seeded From UniProt

complete

part_of

GO:0042597

periplasmic space

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0574
UniProtKB-SubCell:SL-0200

C

Seeded From UniProt

complete

involved_in

GO:0071555

cell wall organization

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0961

P

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Smith, JD et al. (2013) Structural analysis of the role of Pseudomonas aeruginosa penicillin-binding protein 5 in β-lactam resistance. Antimicrob. Agents Chemother. 57 3137-46 PubMed GONUTS page
  2. Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page