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PSEAE:G3XCW9
Contents
| Species (Taxon ID) | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 /JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1). (208964) | |
| Gene Name(s) | ampD (ECO:0000313 with EMBL:AAG07910.1) | |
| Protein Name(s) | Beta-lactamase expression regulator AmpD (ECO:0000313 with EMBL:AAG07910.1) | |
| External Links | ||
| UniProt | G3XCW9 | |
| EMBL | AE004091 | |
| PIR | E83080 | |
| RefSeq | NP_253212.1 WP_003112844.1 | |
| ProteinModelPortal | G3XCW9 | |
| STRING | 208964.PA4522 | |
| PaxDb | G3XCW9 | |
| DNASU | 881105 | |
| EnsemblBacteria | AAG07910 | |
| GeneID | 881105 | |
| KEGG | pae:PA4522 | |
| PseudoCAP | PA4522 | |
| eggNOG | ENOG4108VBV COG3023 | |
| InParanoid | G3XCW9 | |
| KO | K03806 | |
| OMA | FNARPEG | |
| PhylomeDB | G3XCW9 | |
| Proteomes | UP000002438 | |
| GO | GO:0009276 GO:0019867 GO:0008745 GO:0009253 GO:0009254 GO:0033252 | |
| CDD | cd06583 | |
| Gene3D | 3.40.80.10 | |
| InterPro | IPR002502 | |
| Pfam | PF01510 | |
| SMART | SM00644 | |
| SUPFAM | SSF55846 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0008745 |
N-acetylmuramoyl-L-alanine amidase activity |
ECO:0000314 |
F |
Figure 2 shows the results of high performance liquid chromatography of a reaction between AmpD and compound 4. It shows that compound 4 was diminished and that two new compounds labeled 19 and 3 were created. The structure of compounds 19 and 3 were determined through mass spectrometry and indicates that AmpD breaks the amide bond in compound 4. Table one shows the same results for AmpD and compounds 4-9 further justifying the role of AmpD in N-acetylmuramoyl-l-alanine amidase activity. |
complete | |||||
|
involved_in |
GO:0009254 |
peptidoglycan turnover |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10041 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0009253 |
peptidoglycan catabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG13687 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0008745 |
N-acetylmuramoyl-L-alanine amidase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG13687 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0033252 |
regulation of beta-lactamase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0009276 |
Gram-negative-bacterium-type cell wall |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008745 |
N-acetylmuramoyl-L-alanine amidase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008745 |
N-acetylmuramoyl-L-alanine amidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009253 |
peptidoglycan catabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Zhang, W et al. (2013) Reactions of the three AmpD enzymes of Pseudomonas aeruginosa. J. Am. Chem. Soc. 135 4950-3 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Langaee, TY et al. (1998) An ampD gene in Pseudomonas aeruginosa encodes a negative regulator of AmpC beta-lactamase expression. Antimicrob. Agents Chemother. 42 3296-300 PubMed GONUTS page
