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PROVU:Q7A225

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Species (Taxon ID) Proteus vulgaris. (585)
Gene Name(s) higB (ECO:0000313 with EMBL:BAB93823.1)
Protein Name(s) Killer protein (ECO:0000313 with EMBL:BAB93823.1)
External Links
UniProt Q7A225
EMBL AP004237
RefSeq NP_640221.1
WP_011039853.1
PDB 4MCT
4MCX
PDBsum 4MCT
4MCX
GeneID 1238806
InterPro IPR007711
Pfam PF05015

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0008285

negative regulation of cell population proliferation

PMID:8645296[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

GO:0045947

negative regulation of translational initiation

ECO:0000315

P

Figure 1 - Shows that bacteria that expressed HigB did not complete translation.

Missing: reference

involved_in

GO:0030308

negative regulation of cell growth

PMID:8645296[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0017148

negative regulation of translation

PMID:19423702[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0030371

translation repressor activity

PMID:19423702[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0043022

ribosome binding

PMID:19423702[2]

ECO:0000315

mutant phenotype evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006401

RNA catabolic process

PMID:19423702[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0090502

RNA phosphodiester bond hydrolysis, endonucleolytic

PMID:19423702[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004521

endoribonuclease activity

PMID:19423702[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003729

mRNA binding

PMID:19423702[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0006379

mRNA cleavage

PMID:19423702[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

enables

GO:0004519

endonuclease activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0255

F

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0694

F

Seeded From UniProt

complete

enables

GO:0004518

nuclease activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0540

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Tian, QB et al. (1996) A new plasmid-encoded proteic killer gene system: cloning, sequencing, and analyzing hig locus of plasmid Rts1. Biochem. Biophys. Res. Commun. 220 280-4 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 Hurley, JM & Woychik, NA (2009) Bacterial toxin HigB associates with ribosomes and mediates translation-dependent mRNA cleavage at A-rich sites. J. Biol. Chem. 284 18605-13 PubMed GONUTS page