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PORGI:CPG2

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Species (Taxon ID) Porphyromonas gingivalis (strain ATCC BAA-308 / W83). (242619)
Gene Name(s) rgpB (synonyms: prtRII, rgp2)
Protein Name(s) Gingipain R2

Arg-gingipain Gingipain 2 RGP-2

External Links
UniProt P95493
EMBL U85038
AF007124
AE015924
RefSeq NP_904801.1
WP_010956050.1
PDB 1CVR
4IEF
PDBsum 1CVR
4IEF
ProteinModelPortal P95493
SMR P95493
IntAct P95493
MINT MINT-8415911
STRING 242619.PG0506
MEROPS C25.003
PRIDE P95493
EnsemblBacteria AAQ65700
GeneID 2552233
KEGG pgi:PG0506
PATRIC 22978106
eggNOG NOG12793
KO K08589
OMA KENGRMI
OrthoDB EOG6BGNW2
BioCyc PGIN242619:GHX8-458-MONOMER
BRENDA 3.4.22.37
SABIO-RK P95493
EvolutionaryTrace P95493
Proteomes UP000000588
GO GO:0004197
GO:0009405
Gene3D 2.60.40.10
3.40.50.10390
3.40.50.1460
InterPro IPR029030
IPR001769
IPR029031
IPR013783
IPR014756
IPR005536
IPR012600
IPR026444
Pfam PF01364
PF03785
PF08126
SUPFAM SSF81296
TIGRFAMs TIGR04183

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0005509

calcium ion binding

PMID:23558682[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0004198

calcium-dependent cysteine-type endopeptidase activity

PMID:9705298[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

PMID:9705298[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

PMID:9705298[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0004197

cysteine-type endopeptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012600

F

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001769
InterPro:IPR005536

P

Seeded From UniProt

complete

enables

GO:0008233

peptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005536

F

Seeded From UniProt

complete

enables

GO:0008234

cysteine-type peptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001769

F

Seeded From UniProt

complete

enables

GO:0008233

peptidase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0645

F

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0645

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

enables

GO:0008234

cysteine-type peptidase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0788

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0843

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. de Diego, I et al. (2013) Porphyromonas gingivalis virulence factor gingipain RgpB shows a unique zymogenic mechanism for cysteine peptidases. J. Biol. Chem. 288 14287-96 PubMed GONUTS page
  2. 2.0 2.1 2.2 Potempa, J et al. (1998) Comparative properties of two cysteine proteinases (gingipains R), the products of two related but individual genes of Porphyromonas gingivalis. J. Biol. Chem. 273 21648-57 PubMed GONUTS page