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PMID:9386101

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Citation

Yoshida, T, Maulik, N, Engelman, RM, Ho, YS, Magnenat, JL, Rousou, JA, Flack, JE 3rd, Deaton, D and Das, DK (1997) Glutathione peroxidase knockout mice are susceptible to myocardial ischemia reperfusion injury. Circulation 96:II-216-20

Abstract

To test our hypothesis that intracellular antioxidant enzymes constitute a cellular defense against acute stress, we studied myocardial ischemia reperfusion injury in the setting of reduced level of glutathione peroxidase using GSHPx-1 gene knockout mice.

Links

PubMed

Keywords

Animals; Creatine Kinase/secretion; Glutathione Peroxidase/genetics; Glutathione Peroxidase/physiology; Mice; Mice, Knockout; Myocardial Infarction/etiology; Myocardial Reperfusion Injury/etiology

Significance

Annotations

Gene product Qualifier GO ID GO term name Evidence Code with/from Aspect Notes Status


See also

References

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