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PMID:9078378

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Citation

Kobayashi, T and Horiuchi, T (1996) A yeast gene product, Fob1 protein, required for both replication fork blocking and recombinational hotspot activities. Genes Cells 1:465-74

Abstract

In the rRNA gene cluster on the Saccharomyces cerevisiae chromosome XII, a unique site that blocks progression of the replication fork exists in a single unit of the repeats. The site RFB (replication fork blocking) is located within one of two cis-elements present in a nontranscribed region of each repeated unit, which are required for obtaining maximal activity of a hotspot (HOT1) dependent recombination.

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PubMed

Keywords

Amino Acid Sequence; Base Sequence; Chromosome Mapping; DNA Replication; DNA, Fungal/biosynthesis; DNA, Fungal/genetics; DNA-Binding Proteins; Fungal Proteins/genetics; Fungal Proteins/metabolism; Genes, Fungal; Molecular Sequence Data; Multigene Family; Mutation; Recombination, Genetic; Repetitive Sequences, Nucleic Acid; Saccharomyces cerevisiae/genetics; Saccharomyces cerevisiae/metabolism; Saccharomyces cerevisiae Proteins

Significance

Annotations

Gene product Qualifier GO ID GO term name Evidence Code with/from Aspect Notes Status


See also

References

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