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PMID:815243
Citation |
Aharonowitz, Y and Ron, EZ (1976) Translocation in Bacillus subtilis: irreversible inactivation of elongation factor G and viability of a temperature- sensitive mutant. J. Bacteriol. 125:1229-31 |
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Abstract |
A temperature-sensitive mutant of Bacillus subtilis 168 lost its viability irreversibly when grown at temperatures higher than 50 C. It is suggested that this loss of viability is due to irreversible alteration of elongation factor G activity, which was shown in vitro by two different assay methods. |
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Keywords |
Bacillus subtilis/enzymology; Bacillus subtilis/growth & development; Bacillus subtilis/metabolism; Cell-Free System; Chloramphenicol/pharmacology; Chromosome Aberrations; GTP Phosphohydrolase-Linked Elongation Factors/metabolism; Mutation; Peptide Biosynthesis; Peptide Elongation Factors; Puromycin; Temperature; Translocation, Genetic |
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Significance
Annotations
Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|
GO:0003924: GTPase activity |
ECO:0000315: |
F |
Fig: 3 |
complete | ||||
See also
References
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