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PMID:815243

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Citation

Aharonowitz, Y and Ron, EZ (1976) Translocation in Bacillus subtilis: irreversible inactivation of elongation factor G and viability of a temperature- sensitive mutant. J. Bacteriol. 125:1229-31

Abstract

A temperature-sensitive mutant of Bacillus subtilis 168 lost its viability irreversibly when grown at temperatures higher than 50 C. It is suggested that this loss of viability is due to irreversible alteration of elongation factor G activity, which was shown in vitro by two different assay methods.

Links

PubMed PMC236208

Keywords

Bacillus subtilis/enzymology; Bacillus subtilis/growth & development; Bacillus subtilis/metabolism; Cell-Free System; Chloramphenicol/pharmacology; Chromosome Aberrations; GTP Phosphohydrolase-Linked Elongation Factors/metabolism; Mutation; Peptide Biosynthesis; Peptide Elongation Factors; Puromycin; Temperature; Translocation, Genetic

Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

BACSU:EFG

GO:0003924: GTPase activity

ECO:0000315:

F

Fig: 3

complete


See also

References

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