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PMID:4903176
Citation |
Eggen, K and Nathans, D (1969) Regulation of protein synthesis directed by coliphage MS2 RNA. II. In vitro repression by phage coat protein. J. Mol. Biol. 39:293-305 |
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Abstract |
No abstract in PubMed |
Links | |
Keywords |
Autoradiography; Binding Sites; Carbon Isotopes; Cell-Free System; Coliphages; Densitometry; Enzyme Repression; Escherichia coli; Histidine/metabolism; Kinetics; Ligases/metabolism; RNA, Messenger/metabolism; Ribonucleases; Threonine/metabolism; Viral Proteins/biosynthesis; Viral Proteins/physiology |
Significance
Annotations
Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
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GO:1904972: negative regulation of viral translation |
ECO:0000314: |
P |
Incubation of MS2 coat protein with RNA showed significantly decreased phage protein production through 14C-labeled proteins and radioautography. The coat protein was shown to have specific inhibitory effect on its homologous RNA, and formed a complex when bound to the RNA. Fig. 5 shows that formation of this complex strongly correlates to inhibitory effect. |
complete | ||||
Notes
See also
References
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