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PMID:3447593
| Citation |
Lundin, LG (1987) A gene (Bmn) controlling beta-mannosidase activity in the mouse is located in the distal part of chromosome 3. Biochem. Genet. 25:603-10 |
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| Abstract |
A gene (Bmn) with a major effect on beta-mannosidase activity in kidney and liver of the house mouse was revealed by assay with the synthetic substrate p-nitrophenyl-beta-D-mannoside. Activity is low in DBA/2J and CSB mice and high in C57BL/6J mice. By the use of the BXD series of recombinant inbred strains and by crosses between C57BL and CSB, it was possible to map the gene to the distal part of chromosome 3 by demonstration of linkage to a gene for cadmium resistance, cdm, as well as to the Adh-3 locus. |
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| Keywords |
Alcohol Dehydrogenase/genetics; Animals; Cadmium/pharmacology; Chromosome Mapping; Female; Genetic Linkage; Kidney/enzymology; Liver/enzymology; Male; Mannosidases/genetics; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Sex Factors; beta-Mannosidase |
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Significance
Annotations
| Gene product | Qualifier | GO ID | GO term name | Evidence Code | with/from | Aspect | Notes | Status |
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See also
References
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