PMID:3257305

Citation	Lumenta, C, Reschofsky, K and Bock, W (1988) Effects of cerebellar retraction on brainstem auditory evoked potentials in an experimental animal model of cerebellopontine angle tumor. Surg Neurol 29:108-14
Abstract	The effects of cerebellar retraction on brainstem auditory evoked potentials (BAEPs) were studied in 15 New Zealand rabbits. In the first series, a Fogarty catheter was placed in the cerebellopontine angle of 5 rabbits. When a balloon volume of 0.2 mL was produced, only the latencies of waves III-V of the ipsilateral side increased. With a volume of 0.4 mL the ipsilateral BAEPs were irreversibly lost and the contralateral one reversibly changed. A volume of 0.6 mL caused loss of the BAEP on both sides and death of the animal. In another series, the cerebellum of 10 rabbits was retracted by a self-retaining retractor laterally to medially, so an approach to the cerebellopontine angle was simulated. With a retraction of up to 36 power units (p) the ipsilateral BAEPs were reversibly changed. A retraction of 54 p caused irreversible loss of wave V on both sides. With 84 p ipsilateral and contralateral waves III-V were immediately lost. The animals died within 7 minutes. Our experimental investigation shows that not only a defined volume in the cerebellopontine angle can cause irreversible impairment of brainstem function, but also uncontrolled retraction of the cerebellum.
Links	PubMed
Keywords	Animals; Brain Stem/physiology; Catheterization; Cerebellar Neoplasms/physiopathology; Cerebellopontine Angle; Cerebellum/pathology; Cerebellum/physiology; Disease Models, Animal; Evoked Potentials, Auditory; Necrosis; Rabbits
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