GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
PMID:3024109
| Citation |
Oh, EY and Grossman, L (1986) The effect of Escherichia coli Uvr protein binding on the topology of supercoiled DNA. Nucleic Acids Res. 14:8557-71 |
|---|---|
| Abstract |
The effects of the binding of the E. coli UvrA and UvrB proteins on the linking number (delta L) of superhelical DNA has been measured. The effects of cofactor ATP structure on UvrAB-nucleoprotein complex formation revealed that nucleotide binding, not hydrolysis, is sufficient to locally unwind the DNA helix of both ultraviolet light-damaged as well as undamaged DNAs. The extent of this unwinding is of the same order of magnitude as the nucleotide distances of the double incision sites generated by the UvrABC endonucleolytic reaction. |
| Links | |
| Keywords |
Bacterial Proteins/metabolism; DNA, Superhelical/metabolism; DNA, Superhelical/radiation effects; Escherichia coli/genetics; Escherichia coli/metabolism; Kinetics; Protein Binding; Ultraviolet Rays |
| edit table |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
See also
References
See Help:References for how to manage references in GONUTS.
