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PMID:3007433

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Citation

Yamaguchi, S, Fujita, H, Ishihara, A, Aizawa, S and Macnab, RM (1986) Subdivision of flagellar genes of Salmonella typhimurium into regions responsible for assembly, rotation, and switching. J. Bacteriol. 166:187-93

Abstract

Three flagellar genes of Salmonella typhimurium (flaAII.2, flaQ, and flaN) were found to be multifunctional, each being associated with four distinct mutant phenotypes: nonflagellate (Fla-), paralyzed (Mot-), nonchemotactic (Che-) with clockwise motor bias, and nonchemotactic (Che-) with counterclockwise motor bias. The distribution of Fla, Mot, and Che mutational sites within each gene was examined. Fla sites were fairly broadly distributed, whereas Mot and Che sites were more narrowly defined. Local subregions rich in sites of one type were not generally rich in sites of another type. Among Che sites, there was little overlap between those corresponding to a clockwise bias and those corresponding to a counterclockwise bias. Our results suggest that within the corresponding gene products there are specialized subregions for flagellar structure, motor rotation, and control of the sense of rotation.

Links

PubMed PMC214575

Keywords

Alleles; Bacterial Proteins/analysis; Chromosome Deletion; Chromosome Mapping; Flagella; Genes, Bacterial; Mutation; Phenotype; Rotation; Salmonella typhimurium/genetics

Significance

Annotations

Gene product Qualifier GO Term Evidence Code with/from Aspect Extension Notes Status

SALTY:FLIG

GO:0071973: bacterial-type flagellum-dependent cell motility

ECO:0000315:

P

Figure 3

complete
CACAO 8704

SALTY:FLIG

involved_in

GO:0071973: bacterial-type flagellum-dependent cell motility

ECO:0000315: mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

See also

References

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