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PMID:2785932
| Citation |
Barber, D, Sánchez-Monge, R, Gómez, L, Carpizo, J, Armentia, A, López-Otín, C, Juan, F and Salcedo, G (1989) A barley flour inhibitor of insect alpha-amylase is a major allergen associated with baker's asthma disease. FEBS Lett. 248:119-22 |
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| Abstract |
A barley salt-soluble protein of 14.5 kDa, which inhibits the alpha-amylase from the insect Tenebrio molitor, has been identified as a major IgE-binding component of sera from baker's asthma patients. The N-terminal amino acid sequence of this protein indicates that it is a member of a previously described family of alpha-amylase/trypsin inhibitors. |
| Links | |
| Keywords |
Allergens/adverse effects; Allergens/isolation & purification; Amino Acid Sequence; Animals; Asthma/chemically induced; Cereals/analysis; Chromatography, High Pressure Liquid; Electrophoresis/methods; Flour/adverse effects; Flour/analysis; Hordeum/adverse effects; Hordeum/analysis; Insects/enzymology; Molecular Sequence Data; Occupational Diseases/chemically induced; Trypsin Inhibitors/adverse effects; Trypsin Inhibitors/isolation & purification; alpha-Amylases/antagonists & inhibitors |
| edit table |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0015066: alpha-amylase inhibitor activity |
ECO:0000314: |
F |
Table 1 |
complete | ||||
|
enables |
GO:0015066: alpha-amylase inhibitor activity |
ECO:0000314: direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
See also
References
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