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Pilatti, L, Boldrin de Paiva, J, Rojas, TC, Leite, JL, Conceição, RA, Nakazato, G and Dias da Silveira, W (2016) The virulence factor ychO has a pleiotropic action in an Avian Pathogenic Escherichia coli (APEC) strain. BMC Microbiol. 16:35
Avian pathogenic Escherichia coli strains cause extraintestinal diseases in birds, leading to substantial economic losses to the poultry industry worldwide. Bacteria that invade cells can overcome the host humoral immune response, resulting in a higher pathogenicity potential. Invasins are members of a large family of outer membrane proteins that allow pathogen invasion into host cells by interacting with specific receptors on the cell surface.
Animals; Chickens; Escherichia coli/genetics; Escherichia coli/metabolism; Escherichia coli/pathogenicity; Escherichia coli Infections/microbiology; Escherichia coli Infections/veterinary; Escherichia coli Proteins/genetics; Escherichia coli Proteins/metabolism; Mutation; Poultry Diseases/microbiology; Virulence; Virulence Factors/genetics; Virulence Factors/metabolism
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Fig. 5 Survival assay. One-day-old broiler chicks showed higher survival rates when infected with Escherichia coli (SEPT362) mutant ∆ychO compared to the E.coli (SEPT362) WT strain
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