GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
PMID:25812456
| Citation |
Chen, X, Zhang, B, Xiao, J, Ju, F, Li, S, Ren, C, An, L, Chen, T, Liu, G, Facey, P, Mullins, JG and Dyson, P (2015) RfiA, a novel PAP2 domain-containing polytopic membrane protein that confers resistance to the FtsZ inhibitor PC190723. Future Microbiol 10:325-35 |
|---|---|
| Abstract |
ABSTRACT Background: As an essential protein for bacterial cell division, the tubulin-like FtsZ protein has been selected as a target for development of next generation antimicrobials. PC190723 is a fluoride-containing benzamide compound developed as a FtsZ inhibitor that selectively inhibits growth of multidrug resistant Gram-positive bacteria. |
| Links |
PubMed Online version:10.2217/fmb.14.131 |
| Keywords |
|
| edit table |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0016020: membrane |
ECO:0000314: |
C |
Figure 2 A shows a Western blot performed with His-tagged RfiA and an anti-His antibody. The antibody only binds to the membrane fraction, not the cystosolic fraction. |
complete | ||||
|
part_of |
GO:0016020: membrane |
ECO:0000314: direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
Notes
See also
References
See Help:References for how to manage references in GONUTS.
