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PMID:24993543
| Citation |
Yin, H, Zhang, X, Li, X, He, Z, Liang, Y, Guo, X, Hu, Q, Xiao, Y, Cong, J, Ma, L, Niu, J and Liu, X (2014) Whole-genome sequencing reveals novel insights into sulfur oxidation in the extremophile Acidithiobacillus thiooxidans. BMC Microbiol. 14:179 |
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| Abstract |
Acidithiobacillus thiooxidans (A. thiooxidans), a chemolithoautotrophic extremophile, is widely used in the industrial recovery of copper (bioleaching or biomining). The organism grows and survives by autotrophically utilizing energy derived from the oxidation of elemental sulfur and reduced inorganic sulfur compounds (RISCs). However, the lack of genetic manipulation systems has restricted our exploration of its physiology. With the development of high-throughput sequencing technology, the whole genome sequence analysis of A. thiooxidans has allowed preliminary models to be built for genes/enzymes involved in key energy pathways like sulfur oxidation. |
| Links |
PubMed PMC4109375 Online version:10.1186/1471-2180-14-179 |
| Keywords |
Acidithiobacillus thiooxidans/genetics; Acidithiobacillus thiooxidans/metabolism; DNA, Bacterial/chemistry; DNA, Bacterial/genetics; Genome, Bacterial; Metabolic Networks and Pathways/genetics; Molecular Sequence Annotation; Molecular Sequence Data; Oxidation-Reduction; Sequence Analysis, DNA; Sulfur/metabolism |
Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
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Notes
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References
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